SCHEMBL22243287

SCHEMBL22243287

CC(C)(C)c1cc(F)nc(Br)c1

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
KDM4E B2RXH2 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
POLB P06746 1/20 0.32
S1PR1 P21453 1/20 0.31
S1PR3 Q99500 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9967860 0.84 GABRA1 (0.42) GABRA1GABRB2KDM4EGAAMAPT
SCHEMBL20958130 0.84 GABRA1 (0.42) GABRA1GABRB2KDM4EGAAMAPT
SCHEMBL19154841 0.76 HMGCR (0.37) GABRA1GABRB2KDM4EGAAMAPT
SCHEMBL11955165 0.76 POLB (0.38) GABRA1GABRB2KDM4EGAAMAPT
SCHEMBL26860342 0.76 POLB (0.38) GABRA1GABRB2KDM4EGAAMAPT
SCHEMBL9007713 0.74 KDM4E (0.38) GABRA1GABRB2KDM4EGAAMAPT
SCHEMBL22956024 0.74 GABRB2 (0.34) GABRA1GABRB2KDM4EGAAMAPT
SCHEMBL179483 0.74 GAA (0.42) GABRA1GABRB2KDM4EGAAMAPT
SCHEMBL7009866 0.70
SCHEMBL29427082 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020149693-A1 RUTHENIUM COMPLEX COMPOUND, LIGAND FOR PRODUCING SAME, AND USE THEREOF 광주과학기술원 2020-07-23 WO disclosed