Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | RAD52 | P43351 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | YWHAG | P61981 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22520171 | 0.86 | ALDH1A1 (0.39) | ALDH1A1POLBMAPTGAASMN1; SMN2 | |
| SCHEMBL30948588 | 0.79 | CA1 (0.45) | ALDH1A1MAPTGAASMN1; SMN2HTT | |
| SCHEMBL15358686 | 0.78 | ALDH1A1 (0.81) | ALDH1A1POLBMAPTGAASMN1; SMN2 | |
| SCHEMBL22246153 | 0.78 | ALDH1A1 (0.51) | ALDH1A1POLBMAPTGAASMN1; SMN2 | |
| SCHEMBL29400276 | 0.77 | ALDH1A1 (0.55) | ALDH1A1MAPTGAASMN1; SMN2HTT | |
| SCHEMBL24832881 | 0.76 | ALDH1A1 (0.48) | ALDH1A1POLBMAPTGAASMN1; SMN2 | |
| SCHEMBL76629 | 0.75 | ALDH1A1 (0.96) | ALDH1A1POLBMAPTGAASMN1; SMN2 | |
| SCHEMBL22246095 | 0.74 | ALDH1A1 (0.54) | ALDH1A1POLBMAPTGAASMN1; SMN2 | |
| SCHEMBL31312874 | 0.74 | MAPT (0.64) | ALDH1A1POLBMAPTGAASMN1; SMN2 | |
| SCHEMBL854657 | 0.74 | MAPT (0.64) | ALDH1A1POLBMAPTGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113302196-B | EGFR inhibitor, composition and application thereof | 贝达药业股份有限公司 | 2023-08-04 | — | — | CN | disclosed |
| US-20220064196-A1 | EGFR Inhibitors, Compositions and Methods Thereof | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2022-03-03 | — | — | US | disclosed |
| WO-2020147702-A1 | EGFR INHIBITORS, COMPOSITIONS AND METHODS THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2020-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220064196-A1 | EGFR Inhibitors, Compositions and Methods Thereof | EGFR, ERBB2, ERBB3 | ALDH1A1 3755/4885POLB 2679/4885MAPT 3194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.