SCHEMBL854657

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31312874	1.00	MAPT (0.64)	MAPTSMN1; SMN2GAAALDH1A1POLB
	SCHEMBL10127901	0.83	MAPT (0.59)	MAPTSMN1; SMN2GAAALDH1A1POLB
	SCHEMBL31312869	0.83	MAPT (0.59)	MAPTSMN1; SMN2GAAALDH1A1POLB
	SCHEMBL31312959	0.83	ALDH1A1 (0.54)	MAPTSMN1; SMN2GAAALDH1A1POLB
	SCHEMBL855383	0.83	ALDH1A1 (0.54)	MAPTSMN1; SMN2GAAALDH1A1POLB
	SCHEMBL14804169	0.81	LGMN (0.45)	MAPTSMN1; SMN2GAAALDH1A1POLB
	SCHEMBL6052395	0.81	GAA (0.50)	MAPTSMN1; SMN2GAAALDH1A1POLB
	SCHEMBL2302770	0.80	LGMN (0.50)	MAPTSMN1; SMN2GAAALDH1A1KDM4E
	SCHEMBL16305337	0.80	LGMN (0.47)	MAPTSMN1; SMN2GAAALDH1A1POLB
	SCHEMBL15358686	0.79	ALDH1A1 (0.81)	MAPTSMN1; SMN2GAAALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.