Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.48 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 2/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13359255 | 0.87 | POLB (0.47) | CYP19A1GGPS1HRH4HRH3L3MBTL1 | |
| SCHEMBL14982736 | 0.87 | CYP19A1 (0.50) | CYP19A1GGPS1HRH4HRH3L3MBTL1 | |
| SCHEMBL19535080 | 0.86 | HRH4 (0.50) | CYP19A1GGPS1HRH4HRH3GBA1 | |
| SCHEMBL3549774 | 0.85 | CYP19A1 (0.62) | CYP19A1GGPS1HRH4HRH3L3MBTL1 | |
| SCHEMBL3546675 | 0.84 | CYP19A1 (0.65) | CYP19A1GGPS1HRH4HRH3L3MBTL1 | |
| SCHEMBL22794232 | 0.84 | CYP19A1 (0.65) | CYP19A1GGPS1HRH4HRH3L3MBTL1 | |
| SCHEMBL22701235 | 0.84 | CYP19A1 (0.65) | CYP19A1GGPS1HRH4HRH3L3MBTL1 | |
| SCHEMBL25836828 | 0.84 | CYP19A1 (0.65) | CYP19A1GGPS1HRH4HRH3L3MBTL1 | |
| SCHEMBL25837226 | 0.84 | CYP19A1 (0.65) | CYP19A1GGPS1HRH4HRH3L3MBTL1 | |
| SCHEMBL5021080 | 0.83 | L3MBTL1 (0.56) | CYP19A1GGPS1HRH4HRH3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020251971-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |
| US-20200232017-A1 | HIGH INTENSITY LABELED REACTANT COMPOSITIONS AND METHODS FOR SEQUENCING | Quantum-Si Incorporated | 2020-07-23 | — | — | US | disclosed |