Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22248413 | 0.92 | HPGD (0.36) | ROCK2KDM1AMAOBRCOR1HPGD | |
| SCHEMBL22248888 | 0.92 | HTR2A (0.33) | ROCK2KCNH2CYP2D6CYP1A2 | |
| SCHEMBL22248665 | 0.91 | KDM1A (0.37) | KDM1AMAOBRCOR1HPGDHDAC3 | |
| SCHEMBL22248357 | 0.91 | ROCK2 (0.35) | ROCK2IKBKETBK1FAAH | |
| SCHEMBL22248664 | 0.90 | HPGD (0.44) | KDM1AMAOBRCOR1HPGDHDAC3 | |
| SCHEMBL22248670 | 0.90 | FAAH (0.36) | ROCK2CYP2D6CYP1A2FAAH | |
| SCHEMBL22235832 | 0.89 | ROCK2 (0.35) | ROCK2KDM1AMAOBRCOR1HPGD | |
| SCHEMBL22248295 | 0.89 | ROCK2 (0.38) | ROCK2FAAH | |
| SCHEMBL22254537 | 0.88 | ROCK2 (0.39) | ROCK2FAAH | |
| SCHEMBL22248411 | 0.87 | CXCR4 (0.39) | MEN1KMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |