Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 6/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22248383 | 0.92 | ROCK2 (0.47) | ROCK2MCHR1PTPN11 | |
| SCHEMBL22248453 | 0.84 | ROCK2 (0.41) | ROCK2MCHR1 | |
| SCHEMBL22248434 | 0.82 | ROCK2 (0.39) | ROCK2 | |
| SCHEMBL22248938 | 0.81 | ROCK2 (0.48) | ROCK2MCHR1 | |
| SCHEMBL22249157 | 0.81 | ROCK2 (0.48) | ROCK2MCHR1 | |
| SCHEMBL22248654 | 0.81 | ROCK2 (0.50) | ROCK2 | |
| SCHEMBL22254520 | 0.81 | ROCK2 (0.48) | ROCK2MCHR1 | |
| SCHEMBL22254166 | 0.81 | ROCK2 (0.51) | ROCK2MCHR1PTPN11GAA | |
| SCHEMBL22254159 | 0.81 | ROCK2 (0.51) | ROCK2MCHR1PTPN11GAA | |
| SCHEMBL25532196 | 0.81 | ROCK2 (0.51) | ROCK2MCHR1PTPN11GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |