Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 5/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 2/20 | 0.32 |
| ▸ | JAK3 | P52333 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.32 |
| ▸ | ALB | P02768 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22248938 | 1.00 | ROCK2 (0.48) | ROCK2MCHR1KCNH2DPP4DPP8 | |
| SCHEMBL22254490 | 0.90 | ROCK2 (0.49) | ROCK2MCHR1KCNH2DPP4DPP8 | |
| SCHEMBL22248937 | 0.89 | ROCK2 (0.47) | ROCK2MCHR1JAK1JAK3LMNA | |
| SCHEMBL22248383 | 0.88 | ROCK2 (0.47) | ROCK2MCHR1DPP4DPP8JAK1 | |
| SCHEMBL22249162 | 0.88 | ROCK2 (0.42) | ROCK2MCHR1KCNH2LMNACACNA1F | |
| SCHEMBL22248950 | 0.88 | ROCK2 (0.42) | ROCK2MCHR1KCNH2LMNACACNA1F | |
| SCHEMBL22248694 | 0.88 | ROCK2 (0.49) | ROCK2MCHR1KCNH2DPP4DPP8 | |
| SCHEMBL22248365 | 0.86 | ROCK2 (0.45) | ROCK2MCHR1KCNH2DPP4DPP8 | |
| SCHEMBL22249164 | 0.85 | ROCK2 (0.47) | ROCK2MCHR1DPP4DPP8JAK1 | |
| SCHEMBL22254520 | 0.85 | ROCK2 (0.48) | ROCK2MCHR1JAK1JAK3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |