Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.34 |
| ▸ | HTR2A | P28223 | 4/20 | 0.30 |
| ▸ | HTR2C | P28335 | 2/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22248671 | 0.88 | MAOB (0.34) | ROCK2 | |
| SCHEMBL22248384 | 0.83 | ROCK2 (0.33) | ROCK2 | |
| SCHEMBL22249021 | 0.78 | HTR2A (0.31) | HTR2AHTR2C | |
| SCHEMBL22248386 | 0.72 | ROCK2 (0.33) | ROCK2 | |
| SCHEMBL22248369 | 0.72 | MAOB (0.33) | ROCK2 | |
| SCHEMBL25553706 | 0.72 | HTR2A (0.37) | ROCK2HTR2AHTR2C | |
| SCHEMBL25532112 | 0.72 | HTR2A (0.37) | ROCK2HTR2AHTR2C | |
| SCHEMBL22248653 | 0.70 | ROCK2 (0.34) | ROCK2 | |
| SCHEMBL22248391 | 0.70 | ROCK2 (0.32) | ROCK2 | |
| SCHEMBL22248693 | 0.70 | MAOB (0.36) | ROCK2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |