Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22248671 | 0.83 | MAOB (0.34) | MAOBADORA1ROCK2 | |
| SCHEMBL22254240 | 0.82 | ROCK2 (0.39) | MAOBADORA1ROCK2NR1H2KCNH2 | |
| SCHEMBL22248369 | 0.82 | MAOB (0.33) | MAOBADORA1ROCK2 | |
| SCHEMBL22248929 | 0.79 | NR1H2 (0.36) | ROCK2NR1H2FAAH | |
| SCHEMBL22249140 | 0.78 | AOC3 (0.39) | MAOBADORA1FAAHAOC3KCNJ1 | |
| SCHEMBL25532120 | 0.77 | NR1H2 (0.41) | ROCK2NR1H2FAAH | |
| SCHEMBL22248962 | 0.73 | ROCK2 (0.31) | ROCK2 | |
| SCHEMBL25532054 | 0.71 | SLC6A4 (0.39) | ROCK2 | |
| SCHEMBL28689621 | 0.71 | PDE3B (0.33) | — | |
| SCHEMBL22248676 | 0.70 | ROCK2 (0.43) | ROCK2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |