Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.32 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | BCR | P11274 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22254509 | 0.86 | AOC3 (0.38) | AOC3TRPV1FLT3MAOBADORA1 | |
| SCHEMBL22249135 | 0.84 | AOC3 (0.37) | AOC3TRPV1FLT3MKNK1MKNK2 | |
| SCHEMBL22249136 | 0.83 | AOC3 (0.37) | AOC3TRPV1FLT3MKNK1MKNK2 | |
| SCHEMBL22249126 | 0.83 | AOC3 (0.37) | AOC3TRPV1FLT3MKNK1MKNK2 | |
| SCHEMBL22254966 | 0.82 | MKNK1 (0.40) | AOC3FLT3MKNK1MKNK2ABL1 | |
| SCHEMBL22248331 | 0.82 | AOC3 (0.37) | AOC3TRPV1MAOBADORA1MKNK1 | |
| SCHEMBL22235345 | 0.82 | FAAH (0.35) | AOC3TRPV1FLT3MKNK1MKNK2 | |
| SCHEMBL30276593 | 0.79 | TRPV1 (0.35) | AOC3TRPV1FLT3CACNA1HPIK3C3 | |
| SCHEMBL30276642 | 0.79 | MKNK1 (0.34) | AOC3FLT3MKNK1MKNK2ABL1 | |
| SCHEMBL22248693 | 0.78 | MAOB (0.36) | AOC3MAOBADORA1FAAHKCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |