Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.36 |
| ▸ | ABL1 | P00519 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | BCR | P11274 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | RET | P07949 | 4/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | YES1 | P07947 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | MELK | Q14680 | 1/20 | 0.33 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.33 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22249136 | 1.00 | AOC3 (0.37) | AOC3MKNK1MKNK2ABL1CYP3A4 | |
| SCHEMBL22235345 | 0.91 | FAAH (0.35) | AOC3MKNK1MKNK2ABL1CYP3A4 | |
| SCHEMBL22254966 | 0.90 | MKNK1 (0.40) | AOC3MKNK1MKNK2ABL1CYP3A4 | |
| SCHEMBL22248722 | 0.89 | FAAH (0.35) | MKNK1MKNK2ABL1BCRFAAH | |
| SCHEMBL22248308 | 0.88 | FAAH (0.34) | FAAHDDR1 | |
| SCHEMBL22235550 | 0.88 | DPP4 (0.33) | FAAHTRPV1 | |
| Hydrochloric Acid SCHEMBL30276478 | 0.88 | FAAH (0.35) | MKNK1MKNK2ABL1BCRFAAH | |
| SCHEMBL22248280 | 0.87 | AOC3 (0.34) | AOC3MKNK1MKNK2FLT3FLT4 | |
| SCHEMBL22248602 | 0.87 | FAAH (0.34) | MKNK1MKNK2ABL1BCRFAAH | |
| SCHEMBL22248606 | 0.87 | FAAH (0.34) | MKNK1MKNK2ABL1BCRFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |