Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.30 |
| ▸ | MC5R | P33032 | 1/20 | 0.30 |
| ▸ | MC3R | P41968 | 1/20 | 0.30 |
| ▸ | MC1R | Q01726 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22235550 | 0.90 | DPP4 (0.33) | FAAHPOLBUSP25 | |
| SCHEMBL22254963 | 0.89 | FAAH (0.35) | FAAHHTR2CHTR2BMAPK8SIGMAR1 | |
| SCHEMBL22248329 | 0.88 | ROCK2 (0.38) | FAAHPOLBROCK2CA12CA1 | |
| SCHEMBL22248341 | 0.88 | ROCK2 (0.38) | FAAHPOLBROCK2CA12CA1 | |
| SCHEMBL22235671 | 0.88 | ROCK2 (0.38) | FAAHPOLBROCK2CA12CA1 | |
| SCHEMBL22248311 | 0.88 | ROCK2 (0.38) | FAAHPOLBROCK2CA12CA1 | |
| SCHEMBL22249150 | 0.88 | ROCK2 (0.38) | FAAHPOLBROCK2CA12CA1 | |
| SCHEMBL22249136 | 0.88 | AOC3 (0.37) | FAAHDDR1 | |
| SCHEMBL22249126 | 0.88 | AOC3 (0.37) | FAAHDDR1 | |
| SCHEMBL22248869 | 0.87 | FAAH (0.34) | FAAHPOLBEPHX2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |