Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.33 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8986538 | 0.79 | CA2 (0.36) | CA2CHKACA12CA1CA9 | |
| SCHEMBL18912338 | 0.74 | CA2 (0.45) | CA2CHKACA12CA1CA9 | |
| SCHEMBL29322932 | 0.73 | CA2 (0.41) | CA2CHKACA12CA1CA9 | |
| SCHEMBL21240931 | 0.72 | HPGD (0.38) | CA2CHKACA12CA1CA9 | |
| SCHEMBL8203057 | 0.71 | CA2 (0.33) | CA2CHKACA12CA1CA9 | |
| SCHEMBL22248571 | 0.69 | GAA (0.41) | CA2CHKACA12CA1CA9 | |
| SCHEMBL8267139 | 0.69 | — | — | |
| SCHEMBL610815 | 0.69 | — | — | |
| SCHEMBL16796447 | 0.68 | CA2 (0.38) | CA2CHKACA12CA1CA9 | |
| SCHEMBL18914399 | 0.68 | CHRNB2 (0.40) | CA2CHKACA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |