Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | ALB | P02768 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.30 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.30 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22248383 | 0.81 | ROCK2 (0.47) | ROCK2DPP4CACNA1FLMNAALB | |
| SCHEMBL22248453 | 0.79 | ROCK2 (0.41) | ROCK2 | |
| SCHEMBL22249158 | 0.79 | ROCK2 (0.33) | ROCK2 | |
| SCHEMBL22248381 | 0.79 | ROCK2 (0.35) | ROCK2CACNA1FLMNAALBMAPT | |
| SCHEMBL22248434 | 0.77 | ROCK2 (0.39) | ROCK2 | |
| SCHEMBL22248399 | 0.77 | ROCK2 (0.49) | ROCK2 | |
| SCHEMBL22248444 | 0.77 | MCHR1 (0.40) | ROCK2 | |
| Hydrochloric Acid SCHEMBL30276453 | 0.77 | — | — | |
| SCHEMBL22248442 | 0.76 | MCHR1 (0.33) | ROCK2 | |
| SCHEMBL22248398 | 0.74 | ROCK2 (0.36) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |