Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22248961 | 0.87 | ROCK2 (0.37) | ROCK2MCHR1FGFR1 | |
| SCHEMBL22249180 | 0.85 | ROCK2 (0.36) | ROCK2MCHR1 | |
| SCHEMBL22248398 | 0.85 | ROCK2 (0.36) | ROCK2MCHR1 | |
| SCHEMBL22248958 | 0.84 | ROCK2 (0.35) | ROCK2MCHR1 | |
| SCHEMBL22248422 | 0.84 | ROCK2 (0.36) | ROCK2 | |
| SCHEMBL22235897 | 0.84 | HTR4 (0.35) | ROCK2 | |
| SCHEMBL22236020 | 0.84 | HTR4 (0.35) | ROCK2 | |
| SCHEMBL22249171 | 0.83 | ROCK2 (0.37) | ROCK2 | |
| SCHEMBL22248952 | 0.82 | ROCK2 (0.36) | ROCK2MCHR1 | |
| SCHEMBL22248365 | 0.82 | ROCK2 (0.45) | ROCK2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |