Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 4/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.35 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.33 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.33 |
| ▸ | MIF | P14174 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 3/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21058017 | 0.83 | GABRA5 (0.40) | SLCO1B1GABRA5PDE4DPDE7ALPAR1 | |
| SCHEMBL29272615 | 0.83 | SLCO1B1 (0.45) | SLCO1B1GABRA5ABCB11CARM1PRMT6 | |
| SCHEMBL28435767 | 0.81 | KDM4E (0.39) | SLCO1B1ABCB11KDM4EL3MBTL1PDE4D | |
| SCHEMBL22252461 | 0.79 | SLCO1B1 (0.76) | SLCO1B1GABRA5ABCB11LPAR1ABCC3 | |
| SCHEMBL19715654 | 0.77 | SLCO1B1 (0.69) | SLCO1B1GABRA5ABCB11KDM4ELPAR1 | |
| SCHEMBL22252713 | 0.75 | SLCO1B1 (0.61) | SLCO1B1GABRA5ABCB11LPAR1ABCC3 | |
| SCHEMBL22252655 | 0.75 | LPAR1 (0.43) | SLCO1B1GABRA5LPAR1ESR1 | |
| SCHEMBL22252438 | 0.73 | SLCO1B1 (0.51) | SLCO1B1ABCB11 | |
| SCHEMBL24043934 | 0.72 | SLCO1B1 (0.42) | SLCO1B1GABRA5ABCB11PDE4DPDE7A | |
| SCHEMBL21058053 | 0.72 | LPAR1 (0.40) | SLCO1B1GABRA5L3MBTL1LPAR1CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654606-B | Triazole compound as well as preparation method and application thereof | 武汉朗来科技发展有限公司 | 2023-11-07 | — | — | CN | disclosed |
| EP-3912974-A1 | TRIAZOLE COMPOUNDS, AND PREPARATION METHOD THEREOF AND USE | Wuhan LL Science And Technology Development Co., Ltd. (CN) | 2021-11-24 | — | — | EP | disclosed |
| WO-2020147740-A1 | TRIAZOLE COMPOUNDS, AND PREPARATION METHOD THEREOF AND USE | 武汉朗来科技发展有限公司 | 2020-07-23 | — | — | WO | disclosed |