Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 4/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 7/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.35 |
| ▸ | SMARCA2 | P51531 | 5/20 | 0.35 |
| ▸ | SMARCA4 | P51532 | 5/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22252516 | 0.81 | SLCO1B1 (0.47) | KDM4EL3MBTL1PDE4DPDE7ASLCO1B1 | |
| SCHEMBL28432883 | 0.77 | LPAR1 (0.36) | KDM4EL3MBTL1CHRM1MAPTLPAR1 | |
| SCHEMBL28431958 | 0.76 | TSHR (0.40) | KDM4EL3MBTL1CASRMAPT | |
| SCHEMBL29272615 | 0.71 | SLCO1B1 (0.45) | SLCO1B1ABCB11CARM1PRMT6HRH3 | |
| SCHEMBL25278645 | 0.70 | KDM4C (0.35) | — | |
| SCHEMBL22252461 | 0.67 | SLCO1B1 (0.76) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL1836024 | 0.66 | KDM4E (0.52) | KDM4EL3MBTL1CARM1PRMT6HRH3 | |
| SCHEMBL21058017 | 0.66 | GABRA5 (0.40) | PDE4DPDE7ASLCO1B1LPAR1 | |
| SCHEMBL1837026 | 0.65 | KDM4E (0.51) | KDM4EL3MBTL1HRH3 | |
| SCHEMBL1837906 | 0.65 | KDM4E (0.51) | KDM4EL3MBTL1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654606-A | Triazole compound and preparation method and application thereof | 武汉朗来科技发展有限公司 | 2021-04-13 | — | — | CN | disclosed |
| CN-111434653-A | Triazole compound and preparation method and application thereof | 武汉朗来科技发展有限公司 | 2020-07-21 | — | — | CN | disclosed |