Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 6/20 | 0.36 |
| ▸ | MAOA | P21397 | 5/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25541887 | 0.83 | TP53 (0.41) | SLC6A4SLC6A2SLC6A3CYP1A2KCNH2 | |
| SCHEMBL22255214 | 0.73 | SLC6A2 (0.45) | SLC6A4SLC6A2SLC6A3CYP1A2KCNH2 | |
| SCHEMBL22254884 | 0.70 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3CYP1A2KCNH2 | |
| SCHEMBL22249111 | 0.69 | PYCR1 (0.43) | SLC6A4SLC6A2SLC6A3KCNH2ADRA2B | |
| SCHEMBL22255182 | 0.68 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3CYP1A2KCNH2 | |
| SCHEMBL22255190 | 0.68 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3CYP1A2KCNH2 | |
| SCHEMBL25541878 | 0.68 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3CYP1A2KCNH2 | |
| SCHEMBL13503177 | 0.67 | CYP1A2 (0.38) | SLC6A4SLC6A2SLC6A3CYP1A2KCNH2 | |
| SCHEMBL25541888 | 0.67 | KCNH2 (0.41) | SLC6A4SLC6A2SLC6A3CYP1A2KCNH2 | |
| SCHEMBL25531120 | 0.67 | TP53 (0.42) | SLC6A4SLC6A2SLC6A3CYP1A2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150385-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |