Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.36 |
| ▸ | MAOB | P27338 | 8/20 | 0.36 |
| ▸ | MAOA | P21397 | 6/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22255190 | 1.00 | SLC6A4 (0.38) | SLC6A4ADRA2BADRA2CADRA1AOPRK1 | |
| SCHEMBL25541878 | 0.88 | SLC6A4 (0.38) | SLC6A4ADRA2BADRA2CADRA1AOPRK1 | |
| SCHEMBL25541874 | 0.85 | TP53 (0.40) | SLC6A4ADRA2BADRA2CADRA1AOPRK1 | |
| SCHEMBL22254875 | 0.83 | CYP2D6 (0.37) | SLC6A4CYP2D6 | |
| SCHEMBL25554413 | 0.73 | ROCK2 (0.36) | — | |
| SCHEMBL22255196 | 0.72 | SLC6A4 (0.35) | SLC6A4ADRA2BADRA2CADRA1AOPRK1 | |
| SCHEMBL22255184 | 0.72 | SIGMAR1 (0.53) | SLC6A4SIGMAR1CYP1A2CYP2D6TSHR | |
| SCHEMBL22255188 | 0.72 | SIGMAR1 (0.53) | SLC6A4SIGMAR1CYP1A2CYP2D6TSHR | |
| SCHEMBL25531108 | 0.71 | SIGMAR1 (0.41) | SLC6A4ADRA2BADRA2CADRA1AOPRK1 | |
| SCHEMBL25531104 | 0.71 | SIGMAR1 (0.41) | SLC6A4ADRA2BADRA2CADRA1AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150385-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |