Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.41 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.37 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | F2R | P25116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15970179 | 0.81 | GRIN2B (0.48) | HRH3HRH4AGTR2SLC6A4NAAA | |
| SCHEMBL22255224 | 0.77 | CNR2 (0.41) | PYCR1IDO1CNR1CNR2TP53 | |
| SCHEMBL22255218 | 0.77 | CNR2 (0.41) | PYCR1IDO1CNR1CNR2TP53 | |
| SCHEMBL14850006 | 0.76 | HRH3 (0.49) | HRH3HRH4PYCR1CHIT1CHIA | |
| SCHEMBL8272641 | 0.74 | HRH4 (0.50) | HRH3HRH4AGTR2 | |
| SCHEMBL22255181 | 0.73 | SLC6A2 (0.39) | PYCR1CHIT1CHIAIDO1CNR1 | |
| SCHEMBL16367150 | 0.72 | HRH3 (0.51) | HRH3HRH4PYCR1SLC6A2SLC6A4 | |
| SCHEMBL31097594 | 0.72 | HRH3 (0.51) | HRH3HRH4PYCR1SLC6A2SLC6A4 | |
| SCHEMBL21655001 | 0.71 | HRH3 (0.45) | HRH3HRH4PYCR1CHIT1CHIA | |
| SCHEMBL16367134 | 0.71 | GRIN2B (0.54) | HRH3HRH4KDM4ENAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150385-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |