SCHEMBL2225523

SCHEMBL2225523

O=C(C(=O)c1ccccc1Cl)c1ccccc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 9/20 0.78
CES1 P23141 8/20 0.78
ALDH1A1 P00352 1/20 0.61
SMO Q99835 1/20 0.53
POLB P06746 2/20 0.52
RAB9A P51151 2/20 0.50
HPGD P15428 2/20 0.50
NPC1 O15118 1/20 0.50
GAA P10253 1/20 0.50
PKM P14618 1/20 0.50
NFKB1 P19838 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
KCNK3 O14649 1/20 0.49
KCNK9 Q9NPC2 1/20 0.49
ERCC5 P28715 1/20 0.48
FEN1 P39748 1/20 0.48
TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29468149 1.00 CES2 (0.78) CES2CES1ALDH1A1SMOPOLB
Urea SCHEMBL28476564 0.94 CES2 (0.69) CES2CES1ALDH1A1SMOPOLB
SCHEMBL4954501 0.91 CES2 (0.64) CES2CES1ALDH1A1SMOPOLB
Acrylic Acid SCHEMBL27571648 0.89 CES2 (0.62) CES2CES1ALDH1A1SMOPOLB
SCHEMBL2156567 0.89 CES2 (1.00) CES2CES1ALDH1A1SMOPOLB
SCHEMBL6317444 0.89 CES2 (1.00) CES2CES1ALDH1A1SMOPOLB
SCHEMBL31544074 0.89 CES2 (1.00) CES2CES1ALDH1A1SMOPOLB
SCHEMBL10808749 0.88 CES2 (0.72) CES2CES1ALDH1A1POLBRAB9A
SCHEMBL2156437 0.88 CES2 (0.72) CES2CES1ALDH1A1POLBRAB9A
SCHEMBL5076702 0.86 TSHR (0.62) CES2CES1ALDH1A1SMOKCNK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116200881-B Heterocyclic aramid nanofiber membrane and preparation method thereof 四川大学 2024-12-24 CN claimed
CN-116200881-A Heterocyclic aramid nanofiber membrane and preparation method thereof 四川大学 2023-06-02 CN claimed
CN-111249929-B Click chemical grafting coordination polyamide-polyimide coal bed gas deoxidation separation membrane 太原理工大学 2022-03-11 CN claimed
US-20250243310-A1 ANION EXCHANGE BRANCHED CO-POLYMER WITH POLY(ARYL) AND A BRANCHED COMPOUND AND QUINUCLIDINIUM SIDE CHAINS AND SYNTHESIS THEREOF USA FORTESCUE IP INC (US) 2025-07-31 US disclosed
CN-116200881-B Heterocyclic aramid nanofiber membrane and preparation method thereof 四川大学 2024-12-24 CN disclosed
US-20240113333-A1 RECHARGEABLE BATTERY WITH ANION CONDUCTING POLYMER APPLE INC (US) 2024-04-04 US disclosed
US-11888112-B2 Rechargeable battery with anion conducting polymer APPLE INC. (US) 2024-01-30 US disclosed
CN-116200881-A Heterocyclic aramid nanofiber membrane and preparation method thereof 四川大学 2023-06-02 CN disclosed
CN-111249929-B Click chemical grafting coordination polyamide-polyimide coal bed gas deoxidation separation membrane 太原理工大学 2022-03-11 CN disclosed
WO-2020200020-A1 HEXAARYLBIIMIDAZOLE PHOTOINITIATOR AND APPLICATION THEREOF 常州格林感光新材料有限公司 2020-10-08 WO disclosed
US-20200194833-A1 RECHARGEABLE BATTERY WITH ANION CONDUCTING POLYMER APPLE INC. (US) 2020-06-18 US disclosed
US-6156380-A Method for preparing contact mass for organohalosilane synthesis SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-12-05 US disclosed
EP-1018528-A2 Polycarbonate resin and process for producing the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2000-07-12 EP disclosed
EP-0976436-A1 WASTEWATER TREATING AGENT, METHOD FOR WASTEWATER TREATMENT, SLUDGE DEHYDRANT, AND METHOD FOR SLUDGE TREATMENT Sony Corporation (JP) 2000-02-02 EP disclosed
US-5981551-A GRANULOCYTE COLONY-STIMULATING FACTOR MIMETICS; TREATMENT OF NEUTROPENIA SMITHKLINE BEECHAM CORPORATION (US) 1999-11-09 US disclosed
EP-0920314-A1 NON-PEPTIDE G-CSF MIMETICS SMITHKLINE BEECHAM CORPORATION (US) 1999-06-09 EP disclosed
WO-1997044033-A1 NON-PEPTIDE G-CSF MIMETICS SMITHKLINE BEECHAM CORPORATION (US) 1997-11-27 WO disclosed
US-4586996-A Surface hardner for nylon lens TOYO BOSEKI KABUSHIKI KAISHA (JP) 1986-05-06 US disclosed
EP-0054075-B1 CELLULOSE-TREATING AGENT AND PAPER PRODUCTS SIZED THEREWITH SEIKO KAGAKU KOGYO CO., LTD. (JP) 1984-08-22 EP disclosed
US-4009022-A Selective antagonists for triazine herbicides ROHM AND HAAS COMPANY (US) 1977-02-22 US disclosed