Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 1.00 |
| ▸ | CES1 | P23141 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.52 |
| ▸ | FEN1 | P39748 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMO | Q99835 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6317444 | 1.00 | CES2 (1.00) | CES2CES1ALDH1A1POLBCYP1A2 | |
| SCHEMBL31544074 | 1.00 | CES2 (1.00) | CES2CES1ALDH1A1POLBCYP1A2 | |
| SCHEMBL31138026 | 0.90 | CES2 (0.81) | CES2CES1ALDH1A1POLBCYP1A2 | |
| SCHEMBL29468149 | 0.89 | CES2 (0.78) | CES2CES1ALDH1A1POLBCYP1A2 | |
| SCHEMBL2225523 | 0.89 | CES2 (0.78) | CES2CES1ALDH1A1POLBCYP1A2 | |
| SCHEMBL1509797 | 0.87 | CES2 (0.77) | CES2CES1ALDH1A1POLBCYP1A2 | |
| SCHEMBL15180840 | 0.87 | CES2 (0.77) | CES2CES1ALDH1A1POLBCYP1A2 | |
| SCHEMBL31633743 | 0.87 | CES2 (0.77) | CES2CES1ALDH1A1POLBCYP1A2 | |
| SCHEMBL8723940 | 0.87 | CES2 (0.77) | CES2CES1ALDH1A1POLBCYP1A2 | |
| SCHEMBL5060798 | 0.85 | CES2 (0.74) | CES2CES1ALDH1A1POLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016026915-A1 | LIGHT-CURING DENTAL COMPOSITE WITH INCREASING OPACITY | IVOCLAR VIVADENT AG (LI) | 2016-02-25 | — | — | WO | claimed |
| US-7973034-B2 | Ameliorating toxic effects of such as cancer therapy drugs or addictive drug overdose | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2011-07-05 | — | — | US | claimed |
| US-4777190-A | Photopolymerizable composition based on a vinyl compound, a sulfur-containing compound and an α-diketone | MITSUBISHI RAYON COMPANY LIMITED (JP) | 1988-10-11 | — | — | US | claimed |
| US-11963948-B1 | 2-(4-chlorophenyl)-4,5-bis(4-chlorophenyl)-1H-imidazole as an antimicrobial compound | King Faisal University (SA) | 2024-04-23 | — | — | US | disclosed |
| CN-112689646-B | Radiation curable composition for rapid prototyping or rapid manufacturing processes | 古莎有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-115943053-A | Radiation curable compositions for rapid prototyping or rapid manufacturing processes | 古莎有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-109705051-B | 2, 4, 5-trisubstituted oxazole and synthesis method thereof | 湖南城市学院 | 2022-09-23 | — | — | CN | disclosed |
| CN-114845683-A | Aesthetic dental filling material with high depth of cure | 义获嘉伟瓦登特公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-114805757-A | Sulfonated polyphenyl ionomer, preparation method thereof and proton exchange membrane | 中国科学院深圳先进技术研究院 | 2022-07-29 | — | — | CN | disclosed |
| CN-109661410-B | Polymerizable compositions containing acyltin photoinitiators | 义获嘉伟瓦登特公司 | 2021-08-17 | — | — | CN | disclosed |
| WO-2021148667-A1 | AESTHETIC DENTAL FILLING MATERIAL HAVING HIGH CURING DEPTH | IVOCLAR VIVADENT AG (LI) | 2021-07-29 | — | — | WO | disclosed |
| WO-2003051850-A1 | PYRAZINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRAZENECA AB (SE) | 2003-06-26 | — | — | WO | disclosed |
| WO-2003051851-A1 | 5, 6-DIARYL-PYRAZINE-2-AMIDE DERIVATIVES AS CB1 ANTAGONISTS | ASTRAZENECA AB (SE) | 2003-06-26 | — | — | WO | disclosed |
| EP-0197616-B1 | PHOTOPOLYMERIZABLE COMPOSITION AND A PHOTO-INITIATOR SYSTEM | DSM RESINS B.V. (NL) | 1992-08-12 | — | — | EP | disclosed |
| US-4826888-A | STORAGE STABLE, DISCOLORATION INHIBITION | MITSUBISHI RAYON CO., LTD. (JP) | 1989-05-02 | — | — | US | disclosed |
| US-4777190-A | Photopolymerizable composition based on a vinyl compound, a sulfur-containing compound and an α-diketone | MITSUBISHI RAYON COMPANY LIMITED (JP) | 1988-10-11 | — | — | US | disclosed |
| EP-0248954-A1 | Process for reducing the amount of DDT-related impurities in 1,1-bis(chlorophenyl)-2,2,2-trichloro-ethanol | ROHM AND HAAS COMPANY (US) | 1987-12-16 | — | — | EP | disclosed |
| EP-0197616-A1 | Photopolymerizable composition and a photo-initiator system | DSM RESINS B.V. (NL) | 1986-10-15 | — | — | EP | disclosed |
| US-4281125-A | CYCLIZATION | DIAMOND SHAMROCK CORPORATION (US) | 1981-07-28 | — | — | US | disclosed |
| US-3998712-A | ULTRAVIOLET RADIATION; LONG SHELF LIFE | BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) | 1976-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11963948-B1 | 2-(4-chlorophenyl)-4,5-bis(4-chlorophenyl)-1H-imidazole as an antimicrobial compound | IL4, CASP4, TLR4 | CES2 1399/4885CES1 3590/4885ALDH1A1 2347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.