SCHEMBL22255348

SCHEMBL22255348

c1ccc(-c2ccc(-c3ccccc3N(c3ccc(-c4ccc5cc(-c6ccccc6)ccc5c4)cc3)c3cccc4sc5ccccc5c34)cc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
F9 P00740 1/20 0.34
S1PR5 Q9H228 8/20 0.34
S1PR4 O95977 6/20 0.34
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
ALOX5 P09917 1/20 0.32
SLC9A1 P19634 1/20 0.31
CRHR1 P34998 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
HSD17B1 P14061 1/20 0.30
HSD17B2 P37059 1/20 0.30
BACE1 P56817 1/20 0.30
LIMK1 P53667 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27273774 0.98 S1PR5 (0.37) F9S1PR5S1PR4ESR1ESR2
SCHEMBL24841710 0.97 S1PR5 (0.36) F9S1PR5S1PR4ESR1ESR2
SCHEMBL27273779 0.97 S1PR5 (0.36) F9S1PR5S1PR4ESR1ESR2
SCHEMBL23179447 0.97 S1PR5 (0.36) F9S1PR5S1PR4ESR1ESR2
SCHEMBL23180315 0.97 S1PR5 (0.36) F9S1PR5S1PR4ESR1ESR2
SCHEMBL24841751 0.97 S1PR5 (0.36) F9S1PR5S1PR4ESR1ESR2
SCHEMBL22255769 0.97 ESR1 (0.34) F9S1PR5S1PR4ESR1ESR2
SCHEMBL27272317 0.97 S1PR5 (0.33) F9S1PR5S1PR4ESR1ESR2
SCHEMBL24841711 0.94 S1PR5 (0.39) F9S1PR5S1PR4ESR1ESR2
SCHEMBL24841996 0.94 S1PR5 (0.39) F9S1PR5S1PR4ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200235297-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MONOAMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200235297-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MONOAMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SLC18A2, SLC18A1, MAOA F9 2570/4885S1PR5 3891/4885S1PR4 3725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.