SCHEMBL22256121

SCHEMBL22256121

CC(C)c1ccc(N(c2ccc3ccc4c(Br)ccc5ccc2c3c54)c2cccc3c2oc2ccccc23)cc1

nearest known ligand 0.32

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TNKS O95271 1/20 0.32
PARP1 P09874 1/20 0.32
TNKS2 Q9H2K2 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
PARP2 Q9UGN5 1/20 0.32
CYP2C9 P11712 1/20 0.31
NQO1 P15559 1/20 0.31
CRHBP P24387 1/20 0.31
CASP7 P55210 1/20 0.31
CASP6 P55212 1/20 0.31
CRHR2 Q13324 1/20 0.31
HIF1A Q16665 1/20 0.31
CASP3 P42574 1/20 0.30
SENP8 Q96LD8 1/20 0.30
SENP7 Q9BQF6 1/20 0.30
SENP6 Q9GZR1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4079852 0.94 TNKS (0.35) TNKSPARP1TNKS2HDAC6PARP2
SCHEMBL22255992 0.89 ALOX5 (0.36) TNKSPARP1TNKS2HDAC6PARP2
SCHEMBL24425465 0.88 CDC14B (0.31)
SCHEMBL24425488 0.87 TNKS (0.31) TNKSPARP1TNKS2HDAC6PARP2
SCHEMBL18798580 0.86 SMN1; SMN2 (0.31) TNKSPARP1TNKS2HDAC6PARP2
SCHEMBL13171185 0.86 TNKS (0.35) TNKSPARP1TNKS2HDAC6PARP2
SCHEMBL24425496 0.86
SCHEMBL18799373 0.85 TNKS (0.36) TNKSPARP1TNKS2HDAC6PARP2
SCHEMBL4083817 0.85 TNKS (0.34) TNKSPARP1TNKS2HDAC6PARP2
SCHEMBL4089242 0.84 TNKS (0.32) TNKSPARP1TNKS2HDAC6PARP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11335859-B2 Compound, coating composition comprising same, and organic light emitting element comprising same LG CHEM, LTD. 2022-05-17 US disclosed
US-20200235320-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2020-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11335859-B2 Compound, coating composition comprising same, and organic light emitting element comprising same SEM1, CRY1, CD99 TNKS 3857/4885PARP1 2568/4885TNKS2 4082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.