SCHEMBL22256166

SCHEMBL22256166

Brc1ccc2ccc3c(-c4cccc(-c5ccc6ccccc6c5)c4)ccc4ccc1c2c43

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 3/20 0.42
HSD17B2 P37059 3/20 0.42
GSTP1 P09211 1/20 0.41
SIRT2 Q8IXJ6 3/20 0.39
CYP1A2 P05177 4/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
CYP17A1 P05093 1/20 0.37
CYP19A1 P11511 1/20 0.37
CYP11B1 P15538 1/20 0.37
CYP11B2 P19099 1/20 0.37
ERBB2 P04626 1/20 0.37
FYN P06241 1/20 0.37
MAOA P21397 1/20 0.37
ACHE P22303 1/20 0.37
AHR P35869 1/20 0.37
ALOX5 P09917 1/20 0.37
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29950077 0.94 GSTP1 (0.46) HSD17B1HSD17B2GSTP1CYP1A2ESR1
SCHEMBL2789682 0.94 GSTP1 (0.46) HSD17B1HSD17B2GSTP1CYP1A2ESR1
SCHEMBL31488899 0.91 ESR1 (0.43) HSD17B1HSD17B2GSTP1SIRT2CYP1A2
SCHEMBL16632947 0.89 CYP1A2 (0.41) HSD17B1HSD17B2CYP1A2ESR1ESR2
SCHEMBL22255975 0.88 HSD17B1 (0.42) HSD17B1HSD17B2GSTP1SIRT2CYP1A2
SCHEMBL12192934 0.88 HSD17B1 (0.47) HSD17B1HSD17B2GSTP1SIRT2CYP1A2
SCHEMBL27723548 0.85 CYP1A2 (0.39) HSD17B1HSD17B2CYP1A2ESR1ESR2
SCHEMBL5566042 0.85 GSTP1 (0.43) HSD17B1HSD17B2GSTP1SIRT2CYP1A2
SCHEMBL3689351 0.85 GSTP1 (0.43) HSD17B1HSD17B2GSTP1CYP1A2ESR1
SCHEMBL2789566 0.84 GSTP1 (0.52) HSD17B1HSD17B2GSTP1CYP1A2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200235320-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2020-07-23 US disclosed