Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5566042 | 0.94 | GSTP1 (0.43) | GSTP1HDAC4HDAC2HDAC8CYP2A6 | |
| SCHEMBL4926982 | 0.94 | GSTP1 (0.48) | GSTP1HDAC4HDAC2HDAC8CYP2A6 | |
| SCHEMBL2789682 | 0.90 | GSTP1 (0.46) | GSTP1HDAC4HDAC2HDAC8CYP2A6 | |
| SCHEMBL29950077 | 0.90 | GSTP1 (0.46) | GSTP1HDAC4HDAC2HDAC8CYP2A6 | |
| SCHEMBL27663026 | 0.90 | PIM1 (0.41) | GSTP1HDAC4HDAC2HDAC8CYP1A2 | |
| SCHEMBL3689587 | 0.88 | GSTP1 (0.43) | GSTP1HDAC4HDAC2HDAC8CYP2A6 | |
| SCHEMBL3792915 | 0.87 | GSTP1 (0.55) | GSTP1HDAC4HDAC2HDAC8ESR1 | |
| SCHEMBL3687907 | 0.87 | GSTP1 (0.55) | GSTP1HDAC4HDAC2HDAC8ESR1 | |
| SCHEMBL11024611 | 0.85 | ALDH1A1 (0.39) | CYP1A2ERBB2FYNMAOAACHE | |
| SCHEMBL22256166 | 0.85 | HSD17B1 (0.42) | GSTP1HDAC4HDAC2HDAC8CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169274-B2 | Pyrene derivative and organic electroluminescent element using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2015-10-27 | — | — | US | disclosed |
| US-9169274-B2 | Pyrene derivative and organic electroluminescent element using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2015-10-27 | — | — | US | disclosed |
| US-8318995-B2 | Asymmetric pyrene derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2012-11-27 | — | — | US | disclosed |
| US-20120248420-A1 | PYRENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2012-10-04 | — | — | US | disclosed |
| US-20120248420-A1 | PYRENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2012-10-04 | — | — | US | disclosed |
| US-20120168733-A1 | PYRENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2012-07-05 | — | — | US | disclosed |
| US-20120168733-A1 | PYRENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2012-07-05 | — | — | US | disclosed |
| US-20100308718-A1 | ASYMMETRIC PYRENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2010-12-09 | — | — | US | disclosed |
| US-7763761-B2 | Asymmetric pyrene derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2010-07-27 | — | — | US | disclosed |
| EP-1749809-A1 | ASYMMETRIC PYRENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2007-02-07 | — | — | EP | disclosed |
| US-20060154107-A1 | Asymmetric pyrene derivative and organic electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120168733-A1 | PYRENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME | ESR2, AHR, AR | GSTP1 1477/4885HDAC4 2291/4885HDAC2 1338/4885 |
| US-20100308718-A1 | ASYMMETRIC PYRENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME | ESR1, EBPL, JUP | GSTP1 662/4885HDAC4 4622/4885HDAC2 3706/4885 |
| US-20120248420-A1 | PYRENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME | HNRNPA0, AHR, YBX1 | GSTP1 1286/4885HDAC4 3451/4885HDAC2 2122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.