SCHEMBL22256567

SCHEMBL22256567

C/N=C(\I)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.39
CES2 O00748 4/20 0.38
CES1 P23141 4/20 0.38
TSHR P16473 3/20 0.38
ALDH1A1 P00352 2/20 0.38
DAO P14920 1/20 0.38
NAPRT Q6XQN6 1/20 0.38
G6PC1 P35575 1/20 0.36
MAPT P10636 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.35
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 2/20 0.35
F2 P00734 1/20 0.35
F10 P00742 1/20 0.35
F12 P00748 1/20 0.35
F7 P08709 1/20 0.35
F3 P13726 1/20 0.35
PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9914140 0.78 CYP2C19 (0.44) ATMCES2CES1TSHRALDH1A1
SCHEMBL11523631 0.74 F2 (0.40) ATMCES2CES1TSHRALDH1A1
SCHEMBL11523633 0.74 F2 (0.40) ATMCES2CES1TSHRALDH1A1
SCHEMBL862271 0.72 ALDH1A1 (0.45) ATMCES2CES1TSHRALDH1A1
SCHEMBL4547699 0.70 LMNA (0.52) ATMCES2CES1TSHRALDH1A1
SCHEMBL3443700 0.70 LMNA (0.52) ATMCES2CES1TSHRALDH1A1
SCHEMBL3443698 0.70 LMNA (0.52) ATMCES2CES1TSHRALDH1A1
SCHEMBL3067282 0.70 GAA (0.54) ATMCES2CES1TSHRALDH1A1
SCHEMBL3067286 0.70 GAA (0.54) ATMCES2CES1TSHRALDH1A1
SCHEMBL1568142 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020148303-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-07-23 WO disclosed