Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PTPRF | P10586 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21383160 | 0.68 | MEN1 (0.38) | HPGDNPSR1CHRM2CHRM1CHRM3 | |
| SCHEMBL6587062 | 0.68 | HPGD (0.37) | HPGDNPSR1PTPN1MEN1ALOX15 | |
| SCHEMBL28802735 | 0.68 | HPGD (0.41) | HPGDNPSR1CHRM2CHRM1MEN1 | |
| SCHEMBL18918351 | 0.68 | HPGD (0.37) | HPGDNPSR1MEN1ALOX15KMT2A | |
| SCHEMBL31301094 | 0.68 | MEN1 (0.38) | HPGDNPSR1CHRM2CHRM1CHRM3 | |
| SCHEMBL14114151 | 0.68 | HPGD (0.41) | HPGDNPSR1CHRM2CHRM1CHRM3 | |
| SCHEMBL11184460 | 0.68 | GPR84 (0.49) | HPGDNPSR1MEN1ALOX15KMT2A | |
| SCHEMBL16393502 | 0.67 | HTR6 (0.37) | PTPN1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL10411956 | 0.64 | HPGD (0.35) | HPGDNPSR1 | |
| SCHEMBL10721515 | 0.64 | NOTUM (0.45) | HPGDNPSR1ALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011083264-A1 | THIOCHROMAN DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-07-14 | — | — | WO | disclosed |