SCHEMBL22258182

SCHEMBL22258182

C=C(C)C(=O)OCCOC(=O)CCC(=O)C(=O)OCCOC(=O)C(=C)C

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.53
TSHR P16473 4/20 0.47
MAPT P10636 1/20 0.44
BLM P54132 1/20 0.44
ADRA2A P08913 1/20 0.41
ADRA1A P35348 1/20 0.41
TDP1 Q9NUW8 2/20 0.40
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
DGKA P23743 1/20 0.38
ALDH1A1 P00352 2/20 0.38
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
HTR2C P28335 1/20 0.32
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16744077 0.92 THRB (0.61) THRBTSHRMAPTBLMADRA2A
SCHEMBL124287 0.92 THRB (0.61) THRBTSHRMAPTBLMADRA2A
SCHEMBL20691517 0.89 THRB (0.44) THRBTSHRMAPTBLMADRA2A
SCHEMBL1478120 0.86 THRB (0.55) THRBTSHRMAPTBLMADRA2A
SCHEMBL28959481 0.86 THRB (0.66) THRBTSHRMAPTBLMADRA2A
SCHEMBL2466488 0.86 THRB (0.59) THRBTSHRMAPTBLMADRA2A
SCHEMBL31091784 0.85 THRB (0.50) THRBTSHRMAPTBLMADRA2A
Zinc Ion SCHEMBL31091778 0.85 THRB (0.50) THRBTSHRMAPTBLMADRA2A
SCHEMBL10708376 0.85 THRB (0.50) THRBTSHRMAPTBLMADRA2A
SCHEMBL31091783 0.85 THRB (0.50) THRBTSHRMAPTBLMADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11655314-B2 Photoinitiators for light-curable compositions TECHNISCHE UNIVERSITAET WIEN (AT) 2023-05-23 US disclosed
US-11655314-B2 Photoinitiators for light-curable compositions TECHNISCHE UNIVERSITAET WIEN (AT) 2023-05-23 US disclosed
US-11518823-B2 Photoinitiators for light-curable compositions TECHNISCHE UNIVERSITAET WIEN (AT) 2022-12-06 US disclosed
US-20220235153-A1 PHOTOINITIATORS FOR LIGHT-CURABLE COMPOSITIONS TECHNISCHE UNIVERSITAET WIEN (AT) 2022-07-28 US disclosed
US-20200231531-A1 PHOTOINITIATORS FOR LIGHT-CURABLE COMPOSITIONS TECHNISCHE UNIVERSITAET WIEN (AT) 2020-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11655314-B2 Photoinitiators for light-curable compositions OXER1, PPOX, ORC3 THRB 1740/4885TSHR 2459/4885MAPT 2721/4885
US-11518823-B2 Photoinitiators for light-curable compositions OXER1, ORC3, PPOX THRB 1117/4885TSHR 1831/4885MAPT 2699/4885
US-20220235153-A1 PHOTOINITIATORS FOR LIGHT-CURABLE COMPOSITIONS OXER1, PPOX, ORC3 THRB 1740/4885TSHR 2459/4885MAPT 2721/4885
US-20200231531-A1 PHOTOINITIATORS FOR LIGHT-CURABLE COMPOSITIONS OXER1, ORC3, PPOX THRB 1117/4885TSHR 1831/4885MAPT 2699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.