Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.49 |
| ▸ | RELA | Q04206 | 3/20 | 0.49 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22236104 | 0.87 | RXFP1 (0.47) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL22235634 | 0.78 | RXFP1 (0.46) | TP53FLT1 | |
| SCHEMBL22235940 | 0.78 | EGFR (0.65) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL22236222 | 0.77 | RXFP1 (0.49) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL22236099 | 0.77 | NAMPT (0.53) | MAPTNPC1RAB9ATP53MEN1 | |
| SCHEMBL22235681 | 0.77 | FLT3 (0.55) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL22236040 | 0.76 | FLT1 (0.42) | MAPTNPSR1FLT1KDM4E | |
| SCHEMBL22236103 | 0.75 | DDR1 (0.44) | MAPTNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL22235858 | 0.74 | NAMPT (0.46) | SMN1; SMN2TP53MEN1KMT2ALMNA | |
| SCHEMBL13816814 | 0.73 | FLT3 (0.49) | NPC1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150545-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF THE WNT/B-CATENIN SIGNALING PATHWAY | SAMUMED, LLC (US) | 2020-07-23 | — | — | WO | disclosed |