SCHEMBL222589

SCHEMBL222589

CN1C(C)(C)CC(OC(=O)CCC(=O)O)CC1(C)C

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.36
TP53 P04637 1/20 0.35
KMT2A Q03164 2/20 0.35
KDM6B O15054 1/20 0.35
KDM5C P41229 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
PHF8 Q9UPP1 1/20 0.35
KDM2A Q9Y2K7 1/20 0.35
MEN1 O00255 1/20 0.35
GAA P10253 1/20 0.35
TSHR P16473 4/20 0.35
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.33
APEX1 P27695 1/20 0.33
NAAA Q02083 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Suxemerid SCHEMBL2779070 0.93 SMN1; SMN2 (0.39) SMN1; SMN2TP53KMT2AMEN1GAA
SCHEMBL27261571 0.90 SMN1; SMN2 (0.43) SMN1; SMN2TP53KMT2AMEN1GAA
SCHEMBL846324 0.89 NAAA (0.43) SMN1; SMN2KMT2AMEN1GAATSHR
Succinic Acid SCHEMBL31489936 0.87 NAAA (0.52) KMT2AMEN1TSHRALDH1A1NAAA
SCHEMBL13552035 0.87 GAA (0.43) SMN1; SMN2TP53KMT2AMEN1GAA
SCHEMBL18380836 0.87 KMT2A (0.38) SMN1; SMN2TP53KMT2AMEN1GAA
Suxemerid SCHEMBL636796 0.87 SMN1; SMN2 (0.36) SMN1; SMN2TP53KMT2AMEN1GAA
SCHEMBL3630829 0.87 GAA (0.43) SMN1; SMN2TP53KMT2AKDM6BKDM5C
SCHEMBL463020 0.86 SMN1; SMN2 (0.47) SMN1; SMN2TP53KMT2AMEN1GAA
SCHEMBL5649676 0.86 SMN1; SMN2 (0.44) SMN1; SMN2TP53KMT2AMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4244305-A1 PHOTOCHROMIC-DICHROIC ARTICLES Transitions Optical, Ltd. (IE) 2023-09-20 EP disclosed
WO-2022100816-A1 PHOTOCHROMIC-DICHROIC ARTICLES TRANSITIONS OPTICAL, LTD. (IE) 2022-05-19 WO disclosed
EP-2769998-B1 (METH)ACRYLATE COMPOUND, AND PHOTOCHROMIC CURABLE COMPOSITION CONTAINING SAID (METH)ACRYLATE COMPOUND TOKUYAMA CORP (JP) 2016-08-03 EP disclosed
EP-2769998-A1 (METH)ACRYLATE COMPOUND, AND PHOTOCHROMIC CURABLE COMPOSITION CONTAINING SAID (METH)ACRYLATE COMPOUND Tokuyama Corporation (JP) 2014-08-27 EP disclosed
US-20140203226-A1 (METH)ACRYLATE COMPOUND AND PHOTOCHROMIC CURABLE COMPOSITION CONTAINING THE (METH)ACRYLATE COMPOUND TOKUYAMA CORPORATION (JP) 2014-07-24 US disclosed
US-20140203226-A1 (METH)ACRYLATE COMPOUND AND PHOTOCHROMIC CURABLE COMPOSITION CONTAINING THE (METH)ACRYLATE COMPOUND TOKUYAMA CORPORATION (JP) 2014-07-24 US disclosed
CN-101679764-B Low-dust additive and pigment blends with improved color BASF SE 2014-01-29 CN disclosed
WO-2013022605-A1 MESOGENIC STABILIZERS TRANSITIONS OPTICAL, INC. (US) 2013-02-14 WO disclosed
US-8349210-B2 Mesogenic stabilizers TRANSITIONS OPTICAL, INC. (US) 2013-01-08 US disclosed
US-20120003401-A1 MESOGENIC STABILIZERS TRANSITIONS OPTICAL, INC. (US) 2012-01-05 US disclosed
CN-101679764-A Low-dust additive and pigment blends with improved color CIBA HOLDING INC 2010-03-24 CN disclosed
CN-1213078-C Olefine (co) polymer composition and its manufacturing method and catalyst for olefine (co) polymerization and its manufacturing method CHISSO CORP (JP) 2005-08-03 CN disclosed
CN-1146586-C Olefin homopolymer or copolymer composition and process for producing the same �����ɷ� 2004-04-21 CN disclosed
CN-1429850-A Olefine (co) polymer composition and its manufacturing method and catalyst for olefine (co) polymerization and its manufacturing method CHISSO CORP (JP) 2003-07-16 CN disclosed
CN-1191547-A Olefin (co) polymer composition and method for producing same, and catalyst for olefin (co) polymerization and method for producing same CHISSO CORP (JP) 1998-08-26 CN disclosed
US-5496875-A Derivatives of 2,2,6,6-tetramethyl-4-piperidinol for use as light stabilizers, heat stabilizers and oxidation stabilizers for organic materials CIBA-GEIGY CORPORATION (US) 1996-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140203226-A1 (METH)ACRYLATE COMPOUND AND PHOTOCHROMIC CURABLE COMPOSITION CONTAINING THE (METH)ACRYLATE COMPOUND TET1, MGMT, CRYAA SMN1; SMN2 2834/4885TP53 2726/4885KMT2A 296/4885
US-20120003401-A1 MESOGENIC STABILIZERS PYM1, BMI1, C1S SMN1; SMN2 1566/4885TP53 4304/4885KMT2A 375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.