Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2225900 | 1.00 | TAAR1 (0.33) | TAAR1SIGMAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL289970 | 0.77 | EPHX1 (0.39) | TAAR1SIGMAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL334898 | 0.77 | EPHX1 (0.39) | TAAR1SIGMAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL289969 | 0.77 | EPHX1 (0.39) | TAAR1SIGMAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL13594158 | 0.76 | SIGMAR1 (0.44) | TAAR1SIGMAR1SLC6A2MAOASLC6A4 | |
| SCHEMBL592817 | 0.74 | — | — | |
| SCHEMBL2223407 | 0.74 | — | — | |
| SCHEMBL2222636 | 0.74 | — | — | |
| SCHEMBL2222632 | 0.74 | — | — | |
| SCHEMBL2228979 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011087995-A2 | ORGANIC COMPOUNDS | BARRY CLIFTON (US) | 2011-07-21 | — | — | WO | disclosed |