Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289970 | 1.00 | EPHX1 (0.39) | EPHX1MEN1KMT2ASLC6A2TAAR1 | |
| SCHEMBL334898 | 1.00 | EPHX1 (0.39) | EPHX1MEN1KMT2ASLC6A2TAAR1 | |
| SCHEMBL9234671 | 0.81 | AGXT (0.34) | MEN1KMT2ATAAR1CYP2A6CYP1A2 | |
| SCHEMBL3263940 | 0.81 | MEN1 (0.41) | MEN1KMT2ATAAR1 | |
| SCHEMBL9232952 | 0.81 | SLC18A3 (0.35) | TAAR1SIGMAR1 | |
| SCHEMBL3276592 | 0.81 | EPHX1 (0.33) | EPHX1MEN1KMT2ATDP1CYP1A2 | |
| SCHEMBL9234577 | 0.79 | SLC6A4 (0.47) | SLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9090132 | 0.79 | TSHR (0.41) | EPHX1MEN1KMT2ASLC6A2TAAR1 | |
| SCHEMBL6636811 | 0.79 | SRR (0.41) | EPHX1CYP1A2 | |
| SCHEMBL1099896 | 0.78 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024253550-A1 | THE METHOD OF PREPARATION OF THE MEDICINAL FORMULATION OF CLOTRIMAZOLE WITH AMPHIPHILIC COPOLYMER AND ITS APPLICATION IN ANTICANCER THERAPY AND COMBINED ANTICANCER THERAPY WITH NIFURATEL. | Centrum Badań Molekularnych i Makromolekularnych PAN (PL) | 2024-12-12 | — | — | WO | claimed |
| CN-117777048-B | Preparation method of chiral 2-hydroxymethylmorpholine-4-carboxylic acid tert-butyl ester | 上海科利生物医药有限公司 | 2024-09-20 | — | — | CN | claimed |
| CN-117777048-A | Preparation method of chiral 2-hydroxymethylmorpholine-4-carboxylic acid tert-butyl ester | 上海科利生物医药有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-111647200-B | Acetal structure-containing flame retardant and preparation method and application thereof | 中国科学技术大学 | 2021-07-06 | — | — | CN | claimed |
| CN-110327977-B | Aluminum-lithium bimetallic catalyst and preparation method and application thereof | 山西大学 | 2021-05-14 | — | — | CN | claimed |
| EP-2766422-B1 | VULCANISABLE COMPOUNDS ON THE BASIS OF NITRILE RUBBERS CONTAINING EPOXY GROUPS | ARLANXEO DEUTSCHLAND GMBH (DE) | 2017-05-03 | — | — | EP | claimed |
| US-20040186123-A1 | Process for the synthesis of derivatives of 2, 3-dihydro-1, 4-dioxino- [2, 3-f] quinoline | WYETH | 2004-09-23 | — | — | US | claimed |
| US-6693197-B2 | Process for the synthesis of derivatives of 2,3-dihydro-1,4-dioxino- [2,3-f] quinoline | WYETH | 2004-02-17 | — | — | US | claimed |
| EP-1387845-A2 | PROCESSES FOR THE SYNTHESIS OF DERIVATIVES OF 2,3-DIHYDRO-1,4-DIOXINO-(2,3-f) QUINOLINE | Wyeth (US) | 2004-02-11 | — | — | EP | claimed |
| US-20030134222-A1 | Photoresist composition and method of forming pattern using the same | SAMSUNG ELECTRONICS CO., LTD. | 2003-07-17 | — | — | US | claimed |
| US-20020187983-A1 | Process for the synthesis of derivatives of 2, 3-dihydro-1, 4-dioxino- [2, 3-f] quinoline | WYETH | 2002-12-12 | — | — | US | claimed |
| WO-2002092602-A2 | PROCESSES FOR THE SYNTHESIS OF DERIVATIVES OF 2,3-DIHYDRO-1,4-DIOXINO-[2,3-f] QUINOLINE | WYETH (US) | 2002-11-21 | — | — | WO | claimed |
| EP-1114065-A1 | CELLULOSE MICROFIBRILS WITH MODIFIED SURFACE, PREPARATION METHOD AND USE THEREOF | RHODIA CHIMIE (FR) | 2001-07-11 | — | — | EP | claimed |
| WO-2000015667-A1 | CELLULOSE MICROFIBRILS WITH MODIFIED SURFACE, PREPARATION METHOD AND USE THEREOF | RHODIA CHIMIE (FR) | 2000-03-23 | — | — | WO | claimed |
| US-5476917-A | Dispersity of pigments; gloss | KOREA CHEMICAL CO., LTD. (KR) | 1995-12-19 | — | — | US | claimed |
| JP-59076039-A | — | — | None | — | — | JP | disclosed |
| JP-11240877-A | — | — | None | — | — | JP | disclosed |
| JP-S5976039-A | (S)-2,3-DIACETYL-1-BENZYL GLYCEROL | TOA EIYOU KAGAKU KOGYO KK | 1984-04-28 | — | — | JP | disclosed |
| JP-S5976036-A | PREPARATION OF (4S)-4-(P-TOLYL)PENTANAL | TOA EIYOU KAGAKU KOGYO KK | 1984-04-28 | — | — | JP | disclosed |
| JP-S57116060-A | PREPARATION OF (R)-(-)-5- BENZYLOXYMETHYLTETRAHYDROFURAN-2-ONE | KAWAKEN FINE CHEM CO LTD | 1982-07-19 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020187983-A1 | Process for the synthesis of derivatives of 2, 3-dihydro-1, 4-dioxino- [2, 3-f] quinoline | CYP1A1, CYP2F1, CYP1B1 | EPHX1 279/4885MEN1 1400/4885KMT2A 1775/4885 |
| US-20040186123-A1 | Process for the synthesis of derivatives of 2, 3-dihydro-1, 4-dioxino- [2, 3-f] quinoline | CYP1A1, CYP2F1, CYP1B1 | EPHX1 279/4885MEN1 1400/4885KMT2A 1775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.