Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 8/20 | 0.44 |
| ▸ | FNTB | P49356 | 8/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13719556 | 0.89 | FNTA (0.42) | FNTAFNTBNPSR1POLBTSHR | |
| SCHEMBL6215244 | 0.73 | FNTA (0.40) | FNTAFNTBPOLBTSHRALDH1A1 | |
| SCHEMBL7682332 | 0.62 | FNTA (0.47) | FNTAFNTBPOLBTSHRTDP1 | |
| SCHEMBL14688305 | 0.61 | TACR1 (0.32) | — | |
| SCHEMBL4593155 | 0.57 | CHRM5 (0.53) | POLBALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL2146121 | 0.56 | EPHX2 (0.58) | NPSR1ALDH1A1 | |
| SCHEMBL5950255 | 0.56 | KDM4E (0.73) | NPSR1POLBTSHRTDP1ALDH1A1 | |
| SCHEMBL6534174 | 0.56 | KDM4E (0.73) | NPSR1POLBTSHRTDP1ALDH1A1 | |
| SCHEMBL27979494 | 0.56 | HTT (0.88) | NPSR1POLBTSHRALDH1A1KDM4E | |
| SCHEMBL20576295 | 0.56 | ALDH1A1 (0.54) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523664-A1 | COMPOUNDS AND METHODS | Tempero Pharmaceuticals, Inc. (US) | 2012-11-21 | — | — | EP | claimed |
| WO-2011088192-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2011-07-21 | — | — | WO | claimed |
| EP-2523664-A1 | COMPOUNDS AND METHODS | Tempero Pharmaceuticals, Inc. (US) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011088192-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2011-07-21 | — | — | WO | disclosed |