SCHEMBL22260258

SCHEMBL22260258

c1ccc2c(c1)ccc1c3ccc4c5ccccc5c5ccccc5c4c3oc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 1/20 0.52
ARSA P15289 1/20 0.50
CDC25A P30304 1/20 0.50
CDC25C P30307 1/20 0.50
ALDH1A1 P00352 7/20 0.48
HPGD P15428 6/20 0.48
CYP1A2 P05177 5/20 0.48
HSD17B10 Q99714 4/20 0.48
THRB P10828 1/20 0.48
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 6/20 0.45
CYP1A1 P04798 5/20 0.45
CYP1B1 Q16678 5/20 0.45
MAPT P10636 4/20 0.45
HTT P42858 4/20 0.45
TSHR P16473 2/20 0.45
ABCG2 Q9UNQ0 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
ALOX15 P16050 1/20 0.45
PDE5A O76074 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5470220 0.89 HPRT1 (0.57) HPRT1ARSACDC25ACDC25CALDH1A1
SCHEMBL30154375 0.89 HPRT1 (0.57) HPRT1ARSACDC25ACDC25CALDH1A1
SCHEMBL13085233 0.87 HPRT1 (0.70) HPRT1ALDH1A1HPGDCYP1A2HSD17B10
SCHEMBL21431938 0.82 CDC25A (0.41) HPRT1ARSACDC25ACDC25CALDH1A1
SCHEMBL17384095 0.81 ARSA (0.64) HPRT1ARSACDC25ACDC25CALDH1A1
SCHEMBL22260544 0.81 CYP1A1 (0.45) ARSACDC25ACDC25CALDH1A1HPGD
SCHEMBL22260200 0.81 ARSA (0.38) ARSACDC25ACDC25CALDH1A1HPGD
SCHEMBL22260445 0.80 CYP1A1 (0.44) ARSACDC25ACDC25CALDH1A1HPGD
SCHEMBL1697275 0.79 HSD17B10 (0.48) HPRT1ARSACDC25ACDC25CALDH1A1
SCHEMBL16133269 0.78 ARSA (0.47) ARSACDC25ACDC25CALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200235315-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2020-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200235315-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME TRPA1, PIEZO1, SLCO4C1 HPRT1 989/4885ARSA 3697/4885CDC25A 3063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.