Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23970945 | 0.79 | HTT (0.32) | HTTNPSR1HSD17B10DYRK1A | |
| SCHEMBL23619725 | 0.79 | AAK1 (0.32) | HTTNPSR1HSD17B10DYRK1A | |
| SCHEMBL12263231 | 0.79 | HTT (0.32) | HTTNPSR1HSD17B10DYRK1AHRH4 | |
| SCHEMBL22260115 | 0.78 | HTT (0.37) | HTTHSD17B10DYRK1AHRH4 | |
| SCHEMBL21597043 | 0.75 | CCR1 (0.35) | HTTALDH1A1HSP90AA1KMT2ANPSR1 | |
| SCHEMBL29778842 | 0.75 | CCR1 (0.35) | HTTALDH1A1HSP90AA1KMT2ANPSR1 | |
| SCHEMBL10297546 | 0.73 | GABRA1 (0.39) | HTTHSD17B10HPGD | |
| SCHEMBL25255969 | 0.72 | HTT (0.34) | HTTALDH1A1HSP90AA1KMT2ANPSR1 | |
| SCHEMBL30510469 | 0.72 | HTT (0.34) | HTTALDH1A1HSP90AA1KMT2ANPSR1 | |
| SCHEMBL25927992 | 0.72 | HPGD (0.33) | HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200231607-A1 | TRISUBSTITUTEDSILYLHETEROARYLOXYQUINOLINES AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200231607-A1 | TRISUBSTITUTEDSILYLHETEROARYLOXYQUINOLINES AND ANALOGUES | PIK3C3, ERG28, DDT | HTT 3813/4885ALDH1A1 3448/4885HSP90AA1 3464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.