Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.30 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22260141 | 0.87 | KDM4E (0.37) | — | |
| SCHEMBL22260121 | 0.82 | NR1I2 (0.38) | NR1I2TDP1L3MBTL1KCNA5KCNH2 | |
| SCHEMBL20621443 | 0.81 | TDP1 (0.37) | NR1I2TDP1L3MBTL1KCNA5KCNH2 | |
| SCHEMBL21142338 | 0.81 | TDP1 (0.37) | NR1I2TDP1L3MBTL1KCNA5KCNH2 | |
| SCHEMBL23219779 | 0.79 | NR1I2 (0.38) | NR1I2TDP1L3MBTL1KCNA5KCNH2 | |
| SCHEMBL22260101 | 0.79 | NR1I2 (0.38) | NR1I2TDP1L3MBTL1KCNA5KCNH2 | |
| SCHEMBL19405299 | 0.78 | NR1I2 (0.36) | NR1I2TDP1L3MBTL1KCNA5KCNH2 | |
| SCHEMBL18635979 | 0.76 | TDP1 (0.38) | NR1I2TDP1L3MBTL1KCNA5KCNH2 | |
| SCHEMBL18855230 | 0.76 | TDP1 (0.38) | NR1I2TDP1L3MBTL1KCNA5KCNH2 | |
| SCHEMBL18879385 | 0.76 | TDP1 (0.34) | NR1I2TDP1L3MBTL1KCNA5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200231607-A1 | TRISUBSTITUTEDSILYLHETEROARYLOXYQUINOLINES AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200231607-A1 | TRISUBSTITUTEDSILYLHETEROARYLOXYQUINOLINES AND ANALOGUES | PIK3C3, ERG28, DDT | NR1I2 3733/4885TDP1 1169/4885L3MBTL1 1828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.