Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL8108653 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3238836 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL38656856 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL15823844 | 0.94 | — | — | |
| Bicarbonate SCHEMBL7646840 | 0.94 | CA4 (0.60) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL23086807 | 0.94 | — | — | |
| Bicarbonate SCHEMBL30872939 | 0.94 | CA4 (0.60) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL38657395 | 0.88 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL29896261 | 0.88 | — | — | |
| Bicarbonate SCHEMBL1908265 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 548 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122060495-A | Chromium ion single-doped ultra-wideband near infrared fluorescent material, preparation method thereof and LED device | 重庆邮电大学 | 2026-05-19 | — | — | CN | claimed |
| CN-122035922-A | Method for clean production of high purity scandium oxide from crude scandium oxalate | 中冶瑞木新能源科技有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122037931-A | Gallium aluminate near-infrared luminescent material, preparation method thereof and near-infrared LED luminescent device | 重庆邮电大学 | 2026-05-15 | — | — | CN | claimed |
| US-20250388481-A1 | SYSTEMS AND METHODS FOR BENEFICIATION OF BAUXITE RESIDUE | Elementus Minerals, LLC (US) | 2025-12-25 | — | — | US | claimed |
| CN-120004697-A | Preparation method of OrgVO material and application of OrgVO material as secondary battery anode material | 同济大学 | 2025-05-16 | — | — | CN | claimed |
| CN-118385599-B | Rare earth doped tungsten powder for preparing diamond wire and preparation method thereof | 赣州有色冶金研究所有限公司 | 2025-04-01 | — | — | CN | claimed |
| US-12251589-B2 | System for extinguishing fires | MOLEKULE GROUP, INC. (US) | 2025-03-18 | — | — | US | claimed |
| CN-119462111-A | Multi-element rare earth silicate/silicon oxygen carbon nano multiphase ceramic and preparation method thereof | 中南大学 | 2025-02-18 | — | — | CN | claimed |
| CN-119433594-A | Lignin derived carbon-alloy-metal oxide heterojunction catalyst and preparation method thereof | 广西大学 | 2025-02-14 | — | — | CN | claimed |
| CN-119361633-A | High-entropy graphite composite negative electrode material, preparation method thereof, negative electrode and lithium ion battery | 北京理工大学重庆创新中心 | 2025-01-24 | — | — | CN | claimed |
| CN-102179024-B | Fire extinguishing composition for generating fire extinguishing substance through chemical reaction among components at high temperature | SHAN XI J & R FIRE PROT CO LTD | 2012-06-27 | — | — | CN | claimed |
| CN-102179026-B | Fire extinguishing composition generating extinguishant by pyrolysis | SHAANXI J & R FIRE FIGHTING CO | 2012-06-27 | — | — | CN | claimed |
| CN-102179024-A | Fire extinguishing composition for generating fire extinguishing substance through chemical reaction among components at high temperature | SHAN XI J & R FIRE PROT CO LTD | 2011-09-14 | — | — | CN | claimed |
| CN-102179026-A | Fire extinguishing composition generating extinguishant by pyrolysis | SHAANXI J & R FIRE FIGHTING CO | 2011-09-14 | — | — | CN | claimed |
| CN-101700902-B | Method for manufacturing rare earth fluoride | BAOTOU RUIDA RARE EARTH MATERIAL CO LTD | 2011-05-04 | — | — | CN | claimed |
| CN-101700902-A | Method for manufacturing rare earth fluoride | BAOTOU RUIDA RARE EARTH MATERI | 2010-05-05 | — | — | CN | claimed |
| US-20080292520-A1 | FINE PARTICLES CONTAINING RARE EARTH ELEMENT AND FLUORESCENT PROBE USING THE SAME | MATSUURA DAISUKE | 2008-11-27 | — | — | US | claimed |
| US-20050014283-A1 | Fine particles containing rare earth element and fluorescent probe using the same | DAI NIPPON PRINTING CO., LTD. (JP) | 2005-01-20 | — | — | US | claimed |
| CN-1050112-A | Gun cathode and manufacture method thereof | SAMSUNG ELECTRONIC DEVICES (KR) | 1991-03-20 | — | — | CN | claimed |
| CN-85106255-A | METHOD OF EXTRACT SCANDIUM FROM RARE-EARTH MINERAL | — | 1987-02-11 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250388481-A1 | SYSTEMS AND METHODS FOR BENEFICIATION OF BAUXITE RESIDUE | CA2, SLC9A2, CA4 | CA4 3/4885CA1 251/4885FAHD1 1431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.