Phosphoric Acid

Phosphoric Acid

SCHEMBL2226321

O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.[N-]=[N+]=N

nearest known ligand 0.50

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA9 Q16790 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
CA2 P00918 1/20 0.33
SLC34A1 Q06495 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL13738546 1.00 CA1 (0.50) CA1CA6CA5ACA9CA5B
Phosphoric Acid SCHEMBL2645608 1.00
Phosphoric Acid SCHEMBL5104735 0.82
Phosphoric Acid SCHEMBL28069107 0.82
Phosphoric Acid SCHEMBL2226319 0.82 CA1 (0.40) CA1CA9CA2SLC34A1
Pyrophosphoric Acid SCHEMBL13738548 0.79 FDPS (0.62) CA1CA6CA5ACA9CA5B
Phosphoric Acid SCHEMBL27580647 0.78
Phosphoric Acid SCHEMBL27324272 0.78 SLC34A1 (0.43) CA1CA9CA2SLC34A1
Phosphoric Acid SCHEMBL27486017 0.78
Phosphoric Acid SCHEMBL28320521 0.75 CA1 (0.42) CA1CA9CA2SLC34A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118043465-A Methods for using guide RNAs with chemical modifications 安捷伦科技有限公司 2024-05-14 CN disclosed
CN-117945938-A Tris (hydroxymethyl) methylglycine and citrate lipids 川斯勒佰尔公司 2024-04-30 CN disclosed
CN-117430538-A Thioester cationic lipids 川斯勒佰尔公司 2024-01-23 CN disclosed
CN-116867501-A Self-polarizing immune cells 凯瑞斯马治疗公司 2023-10-10 CN disclosed
CN-116549671-A Improved ICE-based lipid nanoparticle formulations for delivery of MRNA 川斯勒佰尔公司 2023-08-08 CN disclosed
CN-110114058-B Improved ICE-based lipid nanoparticle formulations for delivery of MRNA 川斯勒佰尔公司 2023-05-26 CN disclosed
CN-116113422-A mRNA transfection of immune cells 凯瑞斯马治疗公司 2023-05-12 CN disclosed
WO-2011089393-A1 DETECTION OF TARGET NUCLEIC ACIDS BASED ON OLIGONUCLEOTIDE HYBRIDIZATION AND CHEMICAL LIGATION TRILLION GENOMICS LIMITED (GB) 2011-07-28 WO disclosed