SCHEMBL2226329

SCHEMBL2226329

CC1(NC2CC=C(C#N)CC2)CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 1/20 0.38
GRM5 P41594 1/20 0.31
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19908495 0.69 ALDH1A1 (0.39)
SCHEMBL2660429 0.69 ALDH1A1 (0.39)
SCHEMBL2229100 0.66 DPP4 (0.38) DPP4
SCHEMBL15939245 0.66 DRD3 (0.39) DRD3GRM5
SCHEMBL2228847 0.66 DRD3 (0.39) DRD3GRM5
SCHEMBL29843498 0.65 ALDH1A1 (0.39)
SCHEMBL145913 0.65 DRD3 (0.55) DRD3
SCHEMBL24230061 0.65 DPP4 (0.30) DPP4
SCHEMBL11357704 0.64
SCHEMBL2226868 0.64 DPP4 (0.36) DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011091346-A2 POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2011-07-28 WO disclosed