SCHEMBL2228847

SCHEMBL2228847

CC(NC1CC=C(C#N)CC1)[Si](C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 1/20 0.39
GRM5 P41594 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27855262 0.75 DRD3 (0.44) DRD3GRM5
SCHEMBL15939245 0.67 DRD3 (0.39) DRD3GRM5
SCHEMBL2226329 0.66 DRD3 (0.38) DRD3GRM5
SCHEMBL11357704 0.65
SCHEMBL2230178 0.65 RORC (0.30)
SCHEMBL154512 0.64 DRD3 (0.56) DRD3
SCHEMBL17002563 0.63 DRD3 (0.47) DRD3
SCHEMBL2229389 0.62 JAK2 (0.31)
SCHEMBL2227755 0.62 KMT2A (0.41) DRD3GRM5
SCHEMBL820287 0.62 DRD3 (0.46) DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011091346-A2 POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2011-07-28 WO disclosed