Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | SMYD3 | Q9H7B4 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2227171 | 0.97 | LMNA (0.81) | LMNAALDH1A1HTTKMT2ASMYD3 | |
| SCHEMBL2221189 | 0.91 | LMNA (1.00) | LMNAALDH1A1HTTKMT2ASMYD3 | |
| SCHEMBL2228000 | 0.87 | LMNA (0.80) | LMNAALDH1A1HTTKMT2ASMYD3 | |
| SCHEMBL2216711 | 0.87 | LMNA (0.80) | LMNAALDH1A1HTTKMT2ASMYD3 | |
| SCHEMBL15988178 | 0.85 | LMNA (0.76) | LMNAALDH1A1HTTKMT2ASMYD3 | |
| SCHEMBL2228549 | 0.84 | KMT2A (0.73) | LMNAALDH1A1HTTKMT2ASMYD3 | |
| SCHEMBL14635581 | 0.81 | LMNA (0.59) | LMNAALDH1A1HTTKMT2ASMYD3 | |
| SCHEMBL18706162 | 0.81 | MAPT (0.79) | LMNAALDH1A1HTTKMT2ASMYD3 | |
| SCHEMBL2227761 | 0.79 | KMT2A (0.66) | LMNAALDH1A1HTTKMT2ASMYD3 | |
| SCHEMBL14635011 | 0.79 | LMNA (0.69) | LMNAALDH1A1HTTKMT2ASMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011086178-A1 | AMIDOACRIDINE DERIVATIVES USEFUL AS SELECTIVE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7 | HYBRIGENICS SA (FR) | 2011-07-21 | — | — | WO | claimed |
| WO-2011086178-A1 | AMIDOACRIDINE DERIVATIVES USEFUL AS SELECTIVE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7 | HYBRIGENICS SA (FR) | 2011-07-21 | — | — | WO | disclosed |