Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22265177 | 1.00 | EGLN3 (0.44) | EGLN3NLRP3CYP1A2MAPTHTT | |
| SCHEMBL29472445 | 0.82 | NLRP3 (0.55) | EGLN3NLRP3CYP1A2MAPTHTT | |
| SCHEMBL7789025 | 0.76 | KMT2A (0.48) | HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL30390938 | 0.76 | NLRP3 (0.47) | NLRP3CYP1A2MEN1KMT2AALDH1A1 | |
| SCHEMBL30595455 | 0.75 | FDPS (0.45) | NLRP3HTTHDAC1HDAC6 | |
| SCHEMBL14489820 | 0.75 | EGLN3 (0.50) | EGLN3MEN1KMT2AALDH1A1HDAC1 | |
| Hydrochloric Acid SCHEMBL25425659 | 0.73 | EGLN3 (0.49) | EGLN3MEN1KMT2AALDH1A1HDAC1 | |
| SCHEMBL20702684 | 0.73 | EGLN3 (0.52) | EGLN3MEN1KMT2AALDH1A1HDAC1 | |
| SCHEMBL20702682 | 0.73 | EGLN3 (0.52) | EGLN3MEN1KMT2AALDH1A1HDAC1 | |
| SCHEMBL5107263 | 0.71 | EGLN3 (0.50) | EGLN3MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3914351-A1 | CARBAMATE DERIVATIVES AND USES THEREOF | Nodthera Limited (GB) | 2021-12-01 | — | — | EP | disclosed |
| CN-113660983-A | Carbamate derivatives and uses thereof | 诺瑟拉有限公司 | 2021-11-16 | — | — | CN | disclosed |
| WO-2020152361-A1 | CARBAMATE DERIVATIVES AND USES THEREOF | NodThera Limited (GB) | 2020-07-30 | — | — | WO | disclosed |