Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.54 |
| ▸ | PPARG | P37231 | 7/20 | 0.54 |
| ▸ | PPARD | Q03181 | 7/20 | 0.54 |
| ▸ | PPARA | Q07869 | 7/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TLR2 | O60603 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1000074 | 1.00 | FAAH (0.54) | FAAHGPR84PPARGPPARDPPARA | |
| SCHEMBL8160834 | 1.00 | FAAH (0.54) | FAAHGPR84PPARGPPARDPPARA | |
| SCHEMBL28461891 | 0.86 | HSP90AA1 (0.55) | FAAHGPR84PPARGPPARDPPARA | |
| SCHEMBL3981769 | 0.84 | HDAC3 (0.46) | FAAHALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL29171337 | 0.83 | HSP90AA1 (0.52) | FAAHMEN1KMT2AHSP90AA1 | |
| SCHEMBL26597554 | 0.82 | FAAH (0.63) | FAAHGPR84PPARGPPARDPPARA | |
| SCHEMBL6636001 | 0.82 | FAAH (0.63) | FAAHGPR84PPARGPPARDPPARA | |
| SCHEMBL28717438 | 0.81 | HSP90AA1 (0.50) | FAAHMEN1KMT2AFABP3HSP90AA1 | |
| SCHEMBL29028409 | 0.81 | HSP90AA1 (0.71) | FAAHGPR84PPARGPPARDPPARA | |
| SCHEMBL8497574 | 0.81 | HSP90AA1 (0.70) | FAAHGPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200155215-A1 | CRYOPROTECTANT FOR USE WITH A TREATMENT DEVICE FOR IMPROVED COOLING OF SUBCUTANEOUS LIPID-RICH CELLS | ZELTIQ AESTHETICS, INC. | 2020-05-21 | — | — | US | disclosed |
| EP-2012707-B1 | CRYOPROTECTANT FOR USE WITH A TREATMENT DEVICE FOR IMPROVED COOLING OF SUBCUTANEOUS LIPID-RICH CELLS | ZELTIQ AESTHETICS INC (US) | 2020-03-18 | — | — | EP | disclosed |
| US-20140005760-A1 | CRYOPROTECTANT FOR USE WITH A TREATMENT DEVICE FOR IMPROVED COOLING OF SUBCUTANEOUS LIPID-RICH CELLS | ZELTIQ AESTHETICS, INC. (US) | 2014-01-02 | — | — | US | disclosed |
| WO-2011091293-A1 | COMPOSITIONS FOR USE WITH A SYSTEM FOR IMPROVED COOLING OF SUBCUTANEOUS LIPID-RICH TISSUE | ZELTIQ AESTHETICS, INC. (US) | 2011-07-28 | — | — | WO | disclosed |
| EP-2012707-A2 | CRYOPROTECTANT FOR USE WITH A TREATMENT DEVICE FOR IMPROVED COOLING OF SUBCUTANEOUS LIPID-RICH CELLS | Juniper Medical, Inc. (US) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007127924-A2 | CRYOPROTECTANT FOR USE WITH A TREATMENT DEVICE FOR IMPROVED COOLING OF SUBCUTANEOUS LIPID-RICH CELLS | ZELTIQ AESTHETICS, INC. (US) | 2007-11-08 | — | — | WO | disclosed |
| US-20070255362-A1 | CRYOPROTECTANT FOR USE WITH A COOLING DEVICE FOR IMPROVED COOLING OF SUBCUTANEOUS LIPID-RICH CELLS | JUNIPER MEDICAL, INC. (US) | 2007-11-01 | — | — | US | disclosed |