SCHEMBL3981769

SCHEMBL3981769

CCCC(=O)NNCC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 4/20 0.46
HDAC1 Q13547 3/20 0.46
HDAC2 Q92769 3/20 0.46
HDAC8 Q9BY41 2/20 0.46
HDAC6 Q9UBN7 1/20 0.46
FFAR3 O14843 1/20 0.46
ALOX5 P09917 1/20 0.46
CTSD P07339 1/20 0.44
CYP2C19 P33261 2/20 0.42
ALDH1A1 P00352 2/20 0.42
RECQL P46063 2/20 0.42
KDM4E B2RXH2 3/20 0.41
KDM5C P41229 1/20 0.41
EGLN1 Q9GZT9 1/20 0.41
PHF8 Q9UPP1 1/20 0.41
KDM2A Q9Y2K7 1/20 0.41
MAPT P10636 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8160834 0.84 FAAH (0.54) ALDH1A1MEN1KMT2APLA2G2AFAAH
SCHEMBL2226565 0.84 FAAH (0.54) ALDH1A1MEN1KMT2APLA2G2AFAAH
SCHEMBL1000074 0.84 FAAH (0.54) ALDH1A1MEN1KMT2APLA2G2AFAAH
SCHEMBL28799538 0.81 FFAR3 (0.43) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL13301104 0.78
SCHEMBL6634673 0.77 HDAC3 (0.63) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL233413 0.76 FAAH (0.55) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL6416866 0.76 CTSD (0.54) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL8638776 0.75 LDHA (0.35) CYP2C19ALDH1A1KDM4EKDM5CEGLN1
SCHEMBL21176788 0.74 FAAH (0.53) HDAC3HDAC1HDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110055247-A SINGLE-STRANDED NUCLEIC ACID MOLECULE HAVING AMINO ACID BACKBONE 株式会社博纳克 2019-07-26 CN disclosed
US-7501478-B2 Thermoprecipitating polymer containing enzyme specific ligands, process for the preparation thereof, and use thereof for the separation of enzymes COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2009-03-10 US disclosed
US-20050130867-A1 Thermoprecipitating polymer containing enzyme specific ligands, process for the preparation thereof, and use thereof for the separation of enzymes COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH 2005-06-16 US disclosed
US-6867268-B2 Thermoprecipitating polymer containing enzyme specific ligands, process for the preparation thereof, and use thereof for the separation of enzymes COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2005-03-15 US disclosed
US-6605714-B2 Thermoprecipitating polymers; for use in the separation of biopolymers COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-08-12 US disclosed
US-20030027959-A1 Thermoprecipitating polymer containing enzyme specific ligands, process for the preparation thereof, and use thereof for the separation of enzymes COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH 2003-02-06 US disclosed
US-20020098567-A1 Thermoprecipitating polymer containing enzyme specific ligands, process for the preparation thereof, and use thereof for the separation of enzymes COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH 2002-07-25 US disclosed