Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11110890 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KMT2AMAPTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11112147 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL11498026 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL11498703 | 0.76 | ALDH1A1 (0.45) | ALDH1A1KMT2AMAPTNPC1LMNA | |
| SCHEMBL11498027 | 0.74 | ALDH1A1 (0.43) | ALDH1A1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL17737240 | 0.74 | ALDH1A1 (0.73) | ALDH1A1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL11498207 | 0.73 | ALDH1A1 (0.42) | ALDH1A1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL10688855 | 0.72 | PARP16 (0.39) | ALDH1A1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL11310413 | 0.72 | NPC1 (0.56) | ALDH1A1KMT2AMAPTNPC1LMNA | |
| SCHEMBL28207510 | 0.72 | ALDH1A1 (0.51) | ALDH1A1KMT2AMAPTNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1045684-A | — | — | None | — | — | JP | disclosed |
| JP-55047678-A | — | — | None | — | — | JP | disclosed |
| JP-55059183-A | — | — | None | — | — | JP | disclosed |
| CN-101696221-B | Substituted isoxazoles as fungicides | SYNGENTA LTD | 2013-05-29 | — | — | CN | disclosed |
| CN-102731490-A | Substituted isoxazoles as fungicides | SYNGENTA LTD | 2012-10-17 | — | — | CN | disclosed |
| US-7998983-B2 | 3-(2,6-Dichlorophenyl)-4-[(3-pyridyl)hydroxymethyl]-5-trimethysilylisoxazole; crop protection agents to combat or prevent fungal infestations, or to control other pests such as weeds, insects, or acarids | SYNGENTA LIMITED (GB) | 2011-08-16 | — | — | US | disclosed |
| US-7977341-B2 | For crops; 3-(2,6-Dichlorophenyl)-4-[(3-pyridyl)hydroxymethyl]-5-trimethylsilylisoxazole for example | SYNGENTA LIMITED (GB) | 2011-07-12 | — | — | US | disclosed |
| CN-101696221-A | Substituted isoxazoles as fungicides | SYNGENTA LTD | 2010-04-21 | — | — | CN | disclosed |
| US-20080167350-A1 | SUBSTITUTED ISOXAZOLES AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2008-07-10 | — | — | US | disclosed |
| US-20080096843-A1 | Substituted Isoxazoles as Fungicides | SYNGENTA LIMITED (GB) | 2008-04-24 | — | — | US | disclosed |
| US-5376615-A | Pressure sensitive elements containing a salicylic acid resin and a phenolic resin | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-12-27 | — | — | US | disclosed |
| US-5260403-A | Color-developing composition, aqueous suspension of the composition, and color-developing sheet produced using the suspension and suitable for use in pressure-sensitive copying paper | MITSUI TOATSU CHEMICALS, INC. (JP) | 1993-11-09 | — | — | US | disclosed |
| EP-0523697-A1 | Color-developing compositions and their use | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-01-20 | — | — | EP | disclosed |
| EP-0521474-A1 | Colour-developing composition for pressure-sensitive copying paper | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-01-07 | — | — | EP | disclosed |
| EP-0283924-B1 | AQUEOUS SUSPENSION AND PREPARATION METHOD THEREOF | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-01-29 | — | — | EP | disclosed |
| US-4997874-A | Dispersion of metal-modified salicylic acid resin | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-03-05 | — | — | US | disclosed |
| JP-S6445684-A | DESENSITIZING INK | MITSUI TOATSU CHEMICALS | 1989-02-20 | — | — | JP | disclosed |
| EP-0283924-A2 | Aqueous suspension and preparation method thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1988-09-28 | — | — | EP | disclosed |
| JP-S5559183-A | NOVEL 2-PYRIDYL-1-PHTHALAZONE DERIVATIVE | ISHIKAWA MASAYUKI | 1980-05-02 | — | — | JP | disclosed |
| JP-S5547678-A | NOVEL 2-PYRIDYL-1-PHTHALAZONE DERIVATIVE | ISHIKAWA MASAYUKI | 1980-04-04 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167350-A1 | SUBSTITUTED ISOXAZOLES AS FUNGICIDES | CYP4X1, CYP51A1, CYP3A7 | ALDH1A1 211/4885KMT2A 1773/4885MAPT 3024/4885 |
| US-20080096843-A1 | Substituted Isoxazoles as Fungicides | CYP4X1, CYP51A1, CYP3A7 | ALDH1A1 191/4885KMT2A 1843/4885MAPT 2993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.