SCHEMBL2226760

SCHEMBL2226760

OCC(O)(C1CCCCC1)C1CCCCC1

nearest known ligand 0.31

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.31
CYP2D6 P10635 3/20 0.30
CHRM2 P08172 2/20 0.30
CHRM1 P11229 2/20 0.30
CHRM3 P20309 2/20 0.30
KCNH2 Q12809 2/20 0.30
GRIN2D O15399 1/20 0.30
GRIN3B O60391 1/20 0.30
HRH1 P35367 1/20 0.30
GRIN1 Q05586 1/20 0.30
GRIN2A Q12879 1/20 0.30
GRIN2B Q13224 1/20 0.30
GRIN2C Q14957 1/20 0.30
GRIN3A Q8TCU5 1/20 0.30
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30
NFKB1 P19838 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
CHRM4 P08173 1/20 0.30
HTR1A P08908 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alcohol SCHEMBL28368399 0.93 CYP1A2 (0.34) CYP2D6CHRM2CHRM1KCNH2
SCHEMBL29013569 0.89 CYP1A2 (0.32) CYP2D6CHRM2CHRM1KCNH2
SCHEMBL10946626 0.79 CYP2D6 (0.32) CYP2D6CHRM2CHRM1CHRM3KCNH2
SCHEMBL10881574 0.78 CYP2D6 (0.30) CYP2D6CHRM2CHRM1CHRM3KCNH2
Ethyl Acetate SCHEMBL28364559 0.78 ALDH1A1 (0.47) CYP2D6CHRM2CHRM1KCNH2CYP3A4
SCHEMBL21810986 0.76 CHRM2 (0.39) CYP19A1CYP2D6CHRM2CHRM1CHRM3
SCHEMBL7872652 0.76 CYP19A1 (0.30) CYP19A1
SCHEMBL3624573 0.74
SCHEMBL238491 0.74
SCHEMBL7611041 0.74 EPHX1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110878013-A Synthesis method of (trans ) -4-vinyl-4' - [ (E) -1-propenyl ] -bicyclohexane 西安瑞联新材料股份有限公司 2020-03-13 CN claimed
CN-110790650-A Synthesis method of trans-4 '- (4-alkyl phenyl) (1, 1' -dicyclohexyl) -4-ketone 西安瑞联新材料股份有限公司 2020-02-14 CN claimed
CN-103086848-B Dicyclohexylalkyl ether terminal olefines liquid crystal compound and preparation method thereof YANTAI DERUN LIQUID CRYSTAL MATERIALS CO LTD 2014-09-03 CN claimed
CN-110878013-B Synthesis method of (trans ) -4-vinyl-4' - [ (E) -1-propenyl ] -bicyclohexane 西安瑞联新材料股份有限公司 2023-04-28 CN disclosed
CN-112898133-B Preparation method of trans-ketone intermediate 河北迈尔斯通电子材料有限公司 2022-11-15 CN disclosed
CN-112898133-B Preparation method of trans-ketone intermediate 河北迈尔斯通电子材料有限公司 2022-11-15 CN disclosed
CN-113045385-B Method for synthesizing aliphatic pinacol 广东工业大学 2022-08-02 CN disclosed
CN-113045385-A Method for synthesizing aliphatic pinacol 广东工业大学 2021-06-29 CN disclosed
CN-112898133-A Preparation method of trans-ketone intermediate 河北迈尔斯通电子材料有限公司 2021-06-04 CN disclosed
CN-112898133-A Preparation method of trans-ketone intermediate 河北迈尔斯通电子材料有限公司 2021-06-04 CN disclosed
CN-110878013-A Synthesis method of (trans ) -4-vinyl-4' - [ (E) -1-propenyl ] -bicyclohexane 西安瑞联新材料股份有限公司 2020-03-13 CN disclosed
EP-1206449-A1 LACTAM INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE BRISTOL-MYERS SQUIBB COMPANY (US) 2002-05-22 EP disclosed
EP-1196436-A2 PEPTIDE BORONIC ACID INHIBITORS OF HEPATITIS C VIRUS PROTEASE Bristol-Myers Squibb Pharma Company (US) 2002-04-17 EP disclosed
WO-2001007407-A1 LACTAM INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2001-02-01 WO disclosed
WO-2001002424-A2 PEPTIDE BORONIC ACID INHIBITORS OF HEPATITIS C VIRUS PROTEASE DU PONT PHARMACEUTICALS COMPANY (US) 2001-01-11 WO disclosed
US-5792772-A ADMINISTERING 5-HYDROXYALKYL-3,7-DISUBSTITUTED OR NON-SUBSTITUTED PURINE COMPOUND TO TREAT AUTOIMMUNE DISORDERS CELL THERAPEUTICS, INC. (US) 1998-08-11 US disclosed
US-5580874-A THERAPY FOR SIDE EFFECTS OF IMMUNOSUPPRESSIVE AGENTS CELL THERAPEUTICS, INC. (US) 1996-12-03 US disclosed
EP-0584347-A4 ENANTIOMERIC HYDROXYLATED XANTHINE COMPOUNDS. CELL THERAPEUTICS INC (US) 1995-04-26 EP disclosed
EP-0584347-A1 ENANTIOMERIC HYDROXYLATED XANTHINE COMPOUNDS CELL THERAPEUTICS, INC. (US) 1994-03-02 EP disclosed
WO-1993017684-A2 ENANTIOMERIC HYDROXYLATED XANTHINE COMPOUNDS CELL THERAPEUTICS, INC. (US) 1993-09-16 WO disclosed