Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TERT | O14746 | 1/20 | 0.47 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 7/20 | 0.44 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.43 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.43 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22268136 | 0.94 | POLB (0.54) | POLBFUT5P2RY1P2RY2P2RY4 | |
| SCHEMBL22268124 | 0.94 | TERT (0.55) | POLBTERTFUT5STING1P2RY2 | |
| SCHEMBL22268143 | 0.94 | TERT (0.55) | POLBTERTFUT5STING1P2RY2 | |
| SCHEMBL22268138 | 0.94 | POLB (0.50) | POLBTERTFUT5ENPP1P2RY1 | |
| SCHEMBL25580420 | 0.92 | POLB (0.50) | POLBTERTFUT5ENPP1P2RY1 | |
| SCHEMBL25580486 | 0.92 | POLB (0.50) | POLBTERTFUT5ENPP1P2RY1 | |
| SCHEMBL29332122 | 0.90 | POLB (0.59) | POLBFUT5P2RY2P2RY4P2RY6 | |
| SCHEMBL22268144 | 0.88 | TERT (0.55) | POLBTERTSTING1P2RY2P2RY4 | |
| SCHEMBL22268123 | 0.88 | TERT (0.55) | POLBTERTSTING1P2RY2P2RY4 | |
| SCHEMBL18472090 | 0.87 | TERT (0.55) | POLBTERTSTING1P2RY2P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220162598-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-05-26 | — | — | US | disclosed |
| US-10724035-B2 | Oligonucleotide compositions and methods thereof | WAVE LIFE SCIENCES LTD. (SG) | 2020-07-28 | — | — | US | disclosed |