SCHEMBL22268124

SCHEMBL22268124

CO[P@@](=O)(S)OC[C@H]1O[C@@H](n2cnc3c(=O)[nH]c(N)nc32)CC1O[P@@](=O)(S)OC[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)CC1O[P@@](=O)(S)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)CC1C

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 2/20 0.55
▸ DTYMK P23919 4/20 0.53
▸ F2 P00734 2/20 0.51
▸ POLB P06746 1/20 0.44
▸ FUT5 Q11128 1/20 0.42
▸ TK1 P04183 1/20 0.42
▸ P2RY2 P41231 1/20 0.42
▸ P2RY4 P51582 1/20 0.42
▸ P2RY6 Q15077 1/20 0.42
▸ STING1 Q86WV6 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22268143 1.00 TERT (0.55) TERTDTYMKF2POLBFUT5
SCHEMBL22268144 0.94 TERT (0.55) TERTDTYMKF2POLBTK1
SCHEMBL22268123 0.94 TERT (0.55) TERTDTYMKF2POLBTK1
SCHEMBL18472090 0.94 TERT (0.55) TERTDTYMKF2POLBTK1
SCHEMBL22268149 0.94 POLB (0.49) TERTPOLBFUT5P2RY2P2RY4
SCHEMBL18472071 0.93 TERT (0.55) TERTDTYMKF2POLBTK1
SCHEMBL26860402 0.93 TERT (0.55) TERTDTYMKF2POLBTK1
SCHEMBL27000489 0.93 TERT (0.55) TERTDTYMKF2POLBTK1
SCHEMBL27103916 0.93 TERT (0.55) TERTDTYMKF2POLBTK1
SCHEMBL26221013 0.93 TERT (0.55) TERTDTYMKF2POLBTK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220162598-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2022-05-26 — — US disclosed
US-10724035-B2 Oligonucleotide compositions and methods thereof WAVE LIFE SCIENCES LTD. (SG) 2020-07-28 — — US disclosed
Send feedback