Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | TOP1 | P11387 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ARG2 | P78540 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3288071 | 0.79 | MAOB (0.62) | MAOBTOP1KCNH2CA1CA2 | |
| SCHEMBL10801334 | 0.77 | MAOB (0.65) | MAOBTOP1KCNH2CA1CA2 | |
| SCHEMBL22873145 | 0.76 | HTR2A (0.50) | LTA4HCA1CA2IDO1TAAR1 | |
| SCHEMBL20561263 | 0.76 | L3MBTL1 (0.53) | IDO1 | |
| SCHEMBL10961339 | 0.76 | L3MBTL1 (0.53) | IDO1 | |
| SCHEMBL5956337 | 0.75 | MAOB (0.68) | MAOBTOP1KCNH2CA1CA2 | |
| SCHEMBL29263651 | 0.74 | MAOA (0.63) | MAOBIDO1TAAR1MAOA | |
| SCHEMBL27375031 | 0.74 | TSHR (0.54) | LTA4HIDO1TAAR1MAOA | |
| SCHEMBL28461209 | 0.74 | MAOB (0.60) | MAOBTOP1MAOA | |
| SCHEMBL9590160 | 0.73 | MAOB (0.58) | MAOBTOP1KCNH2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3331895-B1 | PYRROLOPYRIMIDINE NUCLEOSIDES AND ANALOGS THEREOF USEFUL AS ANTIVIRAL AGENTS | CHIMERIX INC (US) | 2020-07-29 | — | — | EP | disclosed |